日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Glycerol and Glycerol-3-Phosphate: Multifaceted Metabolites in Metabolism, Cancer, and Other Diseases

甘油和甘油-3-磷酸:在代谢、癌症和其他疾病中发挥多重作用的代谢物

Madiraju, S R Murthy; Possik, Elite; Al-Mulla, Fahd; Nolan, Christopher J; Prentki, Marc

Suppression of adipocyte ABHD6 favors anti-inflammatory and adipogenic programs to preserve adipose tissue fitness in obesity

抑制脂肪细胞ABHD6有利于抗炎和脂肪生成程序,从而在肥胖症中维持脂肪组织的健康。

Poursharifi, Pegah; Attané, Camille; Chenier, Isabelle; Schmitt, Clemence; Lussier, Roxane; Al-Mass, Anfal; Leung, Yat Hei; Oppong, Abel; Dumais, Élizabeth; Flamand, Nicolas; Abu-Farha, Mohamed; Abubaker, Jehad; Al-Mulla, Fahd; Bai, Ying; Zhang, Dongwei; Peyot, Marie-Line; Tchernof, André; Madiraju, S R Murthy; Prentki, Marc

A simplified protocol based on a standardized meal-stimulated beta-cell response to stratify people living with non-insulin-treated type 2 diabetes

一种基于标准化餐后刺激β细胞反应的简化方案,用于对未接受胰岛素治疗的2型糖尿病患者进行分层。

Sun, Cathy J; Lochnan, Heather; Sorisky, Alexander; Shaw, Julie; Ramsay, Timothy; Nolan, Christopher J; Prentki, Marc; Rabasa-Lhoret, Rémi

Essential role of germ cell glycerol-3-phosphate phosphatase for sperm health, oxidative stress control and male fertility in mice

生殖细胞甘油-3-磷酸磷酸酶对小鼠精子健康、氧化应激控制和男性生育能力的重要作用

Abel Oppong, Yat Hei Leung, Anindya Ghosh, Marie-Line Peyot, Marilène Paquet, Carlos Morales, Hugh J Clarke, Fahd Al-Mulla, Alexandre Boyer, S R Murthy Madiraju, Derek Boerboom, Cristian O'Flaherty, Marc Prentki

Adipocyte Angptl8 deletion improves glucose and energy metabolism and obesity associated inflammation in mice

脂肪细胞Angptl8基因缺失可改善小鼠的葡萄糖和能量代谢以及肥胖相关的炎症。

Anindya Ghosh ,Isabelle Chénier ,Yat Hei Leung ,Abel K Oppong ,Marie-Line Peyot ,S R Murthy Madiraju ,Irina Al-Khairi ,Jehad Abubaker ,Fahd Al-Mulla ,Marc Prentki ,Mohamed Abu-Farha

Glycerol 3-phosphate phosphatase/PGPH-2 counters metabolic stress and promotes healthy aging via a glycogen sensing-AMPK-HLH-30-autophagy axis in C. elegans

甘油 3-磷酸磷酸酶/PGPH-2 通过秀丽隐杆线虫中的糖原感应-AMPK-HLH-30-自噬轴抵抗代谢压力并促进健康衰老

Elite Possik, Laura-Lee Klein, Perla Sanjab, Ruyuan Zhu, Laurence Côté, Ying Bai, Dongwei Zhang, Howard Sun, Anfal Al-Mass, Abel Oppong, Rasheed Ahmad, Alex Parker, S R Murthy Madiraju, Fahd Al-Mulla, Marc Prentki

ABHD6 suppression promotes anti-inflammatory polarization of adipose tissue macrophages via 2-monoacylglycerol/PPAR signaling in obese mice

在肥胖小鼠中,ABHD6抑制通过2-单酰甘油/PPAR信号通路促进脂肪组织巨噬细胞的抗炎极化。

Poursharifi, P; Schmitt, C; Chenier, I; Leung, Y H; Oppong, A K; Bai, Y; Klein, L-L; Al-Mass, A; Lussier, R; Abu-Farha, M; Abubaker, J; Al-Mulla, F; Peyot, M-L; Madiraju, S R M; Prentki, M

Ablation of C-type natriuretic peptide/cGMP signaling in fibroblasts exacerbates adverse cardiac remodeling in mice

成纤维细胞中 C 型利钠肽/cGMP 信号的消融加剧了小鼠的心脏不良重塑

Franziska Werner, Estefania Prentki Santos, Konstanze Michel, Hanna Schrader, Katharina Völker, Tamara Potapenko, Lisa Krebes, Marco Abeßer, Dorothe Möllmann, Martin Schlattjan, Hannes Schmidt, Boris V Skryabin, Katarina Špiranec Spes, Kai Schuh, Christopher P Denton, Hideo A Baba, Michaela Kuhn

Hepatic glycerol shunt and glycerol-3-phosphate phosphatase control liver metabolism and glucodetoxification under hyperglycemia

肝甘油分流和甘油-3-磷酸磷酸酶控制高血糖下的肝脏代谢和葡萄糖毒理作用

Anfal Al-Mass, Pegah Poursharifi, Marie-Line Peyot, Roxane Lussier, Isabelle Chenier, Yat Hei Leung, Anindya Ghosh, Abel Oppong, Elite Possik, Yves Mugabo, Rasheed Ahmad, Robert Sladek, S R Murthy Madiraju, Fahd Al-Mulla, Marc Prentki

Glycerol-3-phosphate phosphatase operates a glycerol shunt in pancreatic β-cells that controls insulin secretion and metabolic stress

甘油-3-磷酸磷酸酶在胰岛β细胞中启动甘油旁路,从而控制胰岛素分泌和代谢应激。

Al-Mass, Anfal; Poursharifi, Pegah; Peyot, Marie-Line; Lussier, Roxane; Levens, Emily J; Guida, Julian; Mugabo, Yves; Possik, Elite; Ahmad, Rasheed; Al-Mulla, Fahd; Sladek, Robert; Madiraju, S R Murthy; Prentki, Marc