日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

In Vivo Determinants of Hepatitis C Virus Adaptation and Escape From Neutralizing Antibody AR5A

丙型肝炎病毒适应和逃避中和抗体AR5A的体内决定因素

Velázquez-Moctezuma, Rodrigo; Burm, Rani; Verhoye, Lieven; Collignon, Laura; Holmbeck, Kenn; Giang, Erick; Law, Mansun; Bukh, Jens; Meuleman, Philip; Prentoe, Jannick

Selection and characterization of a broadly neutralizing class of HCV anti-E2 VH1-69 antibodies.

筛选和鉴定一类具有广谱中和作用的HCV抗E2 VH1-69抗体

Soerensen Andreas, Popovic Filip, Olesen Christina Holmboe, Mendez Blanca Lopez, Lohse Brian, Chen Zhaochun, Farci Patrizia, Purcell Robert H, Alter Harvey J, Barfod Lea Klingenberg, Bukh Jens, Prentoe Jannick

Inactivated genotype 1a, 2a and 3a HCV vaccine candidates induced broadly neutralising antibodies in mice

灭活的1a、2a和3a基因型HCV候选疫苗在小鼠体内诱导产生广谱中和抗体。

Alzua, Garazi Pena; Pihl, Anne Finne; Offersgaard, Anna; Duarte Hernandez, Carlos Rene; Duan, Zhe; Feng, Shan; Fahnøe, Ulrik; Sølund, Christina; Weis, Nina; Law, Mansun; Prentoe, Jannick C; Christensen, Jan Pravsgaard; Bukh, Jens; Gottwein, Judith Margarete

Identification of novel neutralizing determinants for protection against HCV

鉴定新型中和决定簇以预防丙型肝炎病毒感染

Alzua, Garazi P; Pihl, Anne F; Offersgaard, Anna; Velázquez-Moctezuma, Rodrigo; Duarte Hernandez, Carlos R; Augestad, Elias H; Fahnøe, Ulrik; Mathiesen, Christian K; Krarup, Henrik; Law, Mansun; Prentoe, Jannick; Bukh, Jens; Gottwein, Judith M

Mechanisms of Hepatitis C Virus Escape from Vaccine-Relevant Neutralizing Antibodies

丙型肝炎病毒逃避疫苗相关中和抗体的机制

Velázquez-Moctezuma, Rodrigo; Augestad, Elias H; Castelli, Matteo; Holmboe Olesen, Christina; Clementi, Nicola; Clementi, Massimo; Mancini, Nicasio; Prentoe, Jannick

Antigenic and immunogenic evaluation of permutations of soluble hepatitis C virus envelope protein E2 and E1 antigens

可溶性丙型肝炎病毒包膜蛋白E2和E1抗原排列组合的抗原性和免疫原性评价

Prentoe, Jannick; Janitzek, Christoph M; Velázquez-Moctezuma, Rodrigo; Goksøyr, Louise; Olsen, Rebecca W; Fanalista, Margherita; Augestad, Elias H; Thrane, Susan; Pihl, Anne F; Gottwein, Judith M; Sander, Adam F; Bukh, Jens

An alternate conformation of HCV E2 neutralizing face as an additional vaccine target

HCV E2中和面的另一种构象可作为额外的疫苗靶点

Tzarum, Netanel; Giang, Erick; Kadam, Rameshwar U; Chen, Fang; Nagy, Kenna; Augestad, Elias H; Velázquez-Moctezuma, Rodrigo; Keck, Zhen-Yong; Hua, Yuanzi; Stanfield, Robyn L; Dreux, Marlene; Prentoe, Jannick; Foung, Steven K H; Bukh, Jens; Wilson, Ian A; Law, Mansun

Global and local envelope protein dynamics of hepatitis C virus determine broad antibody sensitivity.

丙型肝炎病毒包膜蛋白的整体和局部动态变化决定了其对多种抗体的敏感性

Augestad Elias H, Castelli Matteo, Clementi Nicola, Ströh Luisa J, Krey Thomas, Burioni Roberto, Mancini Nicasio, Bukh Jens, Prentoe Jannick

Broadly neutralizing antibodies from an individual that naturally cleared multiple hepatitis C virus infections uncover molecular determinants for E2 targeting and vaccine design

从一位自然清除多次丙型肝炎病毒感染的个体身上提取的广谱中和抗体,揭示了E2靶向和疫苗设计的分子决定因素。

Keck, Zhen-Yong; Pierce, Brian G; Lau, Patrick; Lu, Janine; Wang, Yong; Underwood, Alexander; Bull, Rowena A; Prentoe, Jannick; Velázquez-Moctezuma, Rodrigo; Walker, Melanie R; Luciani, Fabio; Guest, Johnathan D; Fauvelle, Catherine; Baumert, Thomas F; Bukh, Jens; Lloyd, Andrew R; Foung, Steven K H

Hepatitis C Virus Escape Studies of Human Antibody AR3A Reveal a High Barrier to Resistance and Novel Insights on Viral Antibody Evasion Mechanisms

丙型肝炎病毒对人源抗体AR3A的逃逸研究揭示了其高耐药屏障,并为病毒抗体逃逸机制提供了新的见解

Velázquez-Moctezuma, Rodrigo; Galli, Andrea; Law, Mansun; Bukh, Jens; Prentoe, Jannick