日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Dyr726, a brain-penetrant inhibitor of PI3Kα, Type III receptor tyrosine kinases, and WNT signaling.

Dyr726 是一种可穿透血脑屏障的 PI3Kα、III 型受体酪氨酸激酶和 WNT 信号通路抑制剂

Tandon Vasudha, Fistrovich Alessandra, Nogales Joaquina, Ferro Febe, Rokey Samantha N, Cabel Carly, Miller Amy Dunne, Yagel Mary, Duncan Christina, Atmasidha Aditi, Sharma Ira, Wilms Gerrit, Williams Karin, Elliott Richard, Chavez Timothy, Shaw Yeng, McMahon Aidan, Ginn Sean, Basantes L Emilia, Bedard Nathan, Gokhale Vijay, Ellis Nathan, Prescott Alan R, Smith Stuart J, Rahman Ruman, Becker Walter, Read Kevin D, Chalmers Anthony J, Carragher Neil, Masson Glenn R, Montfort William, Thorne Curtis, Hulme Christopher, Banerjee Sourav

Publisher's Note: ZNRF2 is released from membranes by growth factors and, together with ZNRF1, regulates the Na+/K+ATPase

编者按:ZNRF2 由生长因子从细胞膜释放,并与 ZNRF1 共同调节 Na+/K+ATPase。

Hoxhaj, Gerta; Najafov, Ayaz; Toth, Rachel; Campbell, David G; Prescott, Alan R; MacKintosh, Carol

Why are the phenotypes of TRAF6 knock-in and TRAF6 knock-out mice so different?

为什么TRAF6敲入小鼠和TRAF6敲除小鼠的表型如此不同?

Petrova, Tsvetana; Bennett, Kyle; Nanda, Sambit; Strickson, Sam; Scudamore, Cheryl L; Prescott, Alan R; Cohen, Philip

Nucleotide sugar biosynthesis occurs in the glycosomes of procyclic and bloodstream form Trypanosoma brucei

核苷酸糖生物合成发生在锥虫前环型和血液型的糖体中。

Sampaio Guther, Maria Lucia; Prescott, Alan R; Kuettel, Sabine; Tinti, Michele; Ferguson, Michael A J

Brd4-Brd2 isoform switching coordinates pluripotent exit and Smad2-dependent lineage specification

Brd4-Brd2亚型转换协调多能性退出和Smad2依赖的谱系分化

Fernandez-Alonso, Rosalia; Davidson, Lindsay; Hukelmann, Jens; Zengerle, Michael; Prescott, Alan R; Lamond, Angus; Ciulli, Alessio; Sapkota, Gopal P; Findlay, Greg M

High-resolution quantitative proteome analysis reveals substantial differences between phagosomes of RAW 264.7 and bone marrow derived macrophages

高分辨率定量蛋白质组分析揭示了RAW 264.7细胞和骨髓来源巨噬细胞的吞噬体之间存在显著差异

Guo, Manman; Härtlova, Anetta; Dill, Brian D; Prescott, Alan R; Gierliński, Marek; Trost, Matthias

Biochemical analysis of TssK, a core component of the bacterial Type VI secretion system, reveals distinct oligomeric states of TssK and identifies a TssK-TssFG subcomplex.

对细菌 VI 型分泌系统核心成分 TssK 的生化分析揭示了 TssK 的不同寡聚状态,并鉴定出 TssK-TssFG 亚复合物

English Grant, Byron Olwyn, Cianfanelli Francesca R, Prescott Alan R, Coulthurst Sarah J

BslA is a self-assembling bacterial hydrophobin that coats the Bacillus subtilis biofilm

BslA是一种自组装细菌疏水蛋白,可覆盖枯草芽孢杆菌生物膜。

Hobley, Laura; Ostrowski, Adam; Rao, Francesco V; Bromley, Keith M; Porter, Michael; Prescott, Alan R; MacPhee, Cait E; van Aalten, Daan M F; Stanley-Wall, Nicola R

A synthetic system for expression of components of a bacterial microcompartment

用于表达细菌微区室组分的合成系统

Sargent, Frank; Davidson, Fordyce A; Kelly, Ciarán L; Binny, Rachelle; Christodoulides, Natasha; Gibson, David; Johansson, Emelie; Kozyrska, Katarzyna; Lado, Lucia Licandro; MacCallum, Jane; Montague, Rachel; Ortmann, Brian; Owen, Richard; Coulthurst, Sarah J; Dupuy, Lionel; Prescott, Alan R; Palmer, Tracy

Cellular responses to the metal-binding properties of metformin

细胞对二甲双胍金属结合特性的反应

Logie, Lisa; Harthill, Jean; Patel, Kashyap; Bacon, Sandra; Hamilton, D Lee; Macrae, Katherine; McDougall, Gordon; Wang, Huan-Huan; Xue, Lin; Jiang, Hua; Sakamoto, Kei; Prescott, Alan R; Rena, Graham