日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Highly Sensitive, Flow Cytometry-Based Measurement of Intestinal Permeability in Models of Experimental Colitis

基于流式细胞术的高灵敏度实验性结肠炎模型肠道通透性测量

Kevin Tsai, Caixia Ma, Xiao Han, Joannie Allaire, Genelle R Lunken, Shauna M Crowley, Hongbing Yu, Kevan Jacobson, Lijun Xia, John J Priatel, Bruce A Vallance

Tumor-derived GCSF Alters Tumor and Systemic Immune System Cell Subset Composition and Signaling

肿瘤衍生的 GCSF 改变肿瘤和全身免疫系统细胞亚群的组成和信号传导

Israel Matos, Maunish Barvalia, Manreet K Chehal, A Gordon Robertson, Iva Kulic, Jessica A F D Silva, Abhinandan Ranganathan, Amy Short, Yu-Hsuan Huang, Erin Long, John J Priatel, Salim Dhanji, Brad H Nelson, Danielle L Krebs, Kenneth W Harder

Human JAK1 gain of function causes dysregulated myelopoeisis and severe allergic inflammation

人类JAK1功能获得导致骨髓生成失调和严重的过敏性炎症

Catherine M Biggs, Anna Cordeiro-Santanach, Sergey V Prykhozhij, Adam P Deveau, Yi Lin, Kate L Del Bel, Felix Orben, Robert J Ragotte, Aabida Saferali, Sara Mostafavi, Louie Dinh, Darlene Dai, Katja G Weinacht, Kerry Dobbs, Lisa Ott de Bruin, Mehul Sharma, Kevin Tsai, John J Priatel, Richard A Schre

A Germline Mutation in the C2 Domain of PLCγ2 Associated with Gain-of-Function Expands the Phenotype for PLCG2-Related Diseases

与功能获得相关的 PLCγ2 C2 结构域的种系突变扩大了 PLCG2 相关疾病的表型

Taylor Novice, Amina Kariminia, Kate L Del Bel, Henry Lu, Mehul Sharma, Chinten J Lim, Jay Read, Mark Vander Lugt, Mark C Hannibal, David O'Dwyer, Mirie Hosler, Thomas Scharnitz, Jason M Rizzo, Jennifer Zacur, John Priatel, Sayeh Abdossamadi, Alexandra Bohm, Anne Junker, Stuart E Turvey, Kirk R Schu

An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient

变构 MALT1 抑制剂是一种分子校正剂,可挽救免疫缺陷患者的功能

Jean Quancard, Theo Klein, Shan-Yu Fung, Martin Renatus, Nicola Hughes, Laura Israël, John J Priatel, Sohyeong Kang, Michael A Blank, Rosa I Viner, Jutta Blank, Achim Schlapbach, Paul Erbel, Jayachandran Kizhakkedathu, Frédéric Villard, René Hersperger, Stuart E Turvey, Joerg Eder, Frédéric Bornanci

Arp2/3 complex-driven spatial patterning of the BCR enhances immune synapse formation, BCR signaling and B cell activation

Arp2/3 复合物驱动的 BCR 空间模式增强了免疫突触的形成、BCR 信号传导和 B 细胞活化

Madison Bolger-Munro, Kate Choi, Joshua M Scurll, Libin Abraham, Rhys S Chappell, Duke Sheen, May Dang-Lawson, Xufeng Wu, John J Priatel, Daniel Coombs, John A Hammer, Michael R Gold

2B4-SAP signaling is required for the priming of naive CD8(+) T cells by antigen-expressing B cells and B lymphoma cells

2B4-SAP信号通路是抗原表达B细胞和B淋巴瘤细胞启动初始CD8(+) T细胞所必需的。

Huang, Yu-Hsuan; Tsai, Kevin; Tan, Sara Y; Kang, Sohyeong; Ford, Mandy L; Harder, Kenneth W; Priatel, John J

Pre-diagnostic genotyping identifies T1D subjects with impaired Treg IL-2 signaling and an elevated proportion of FOXP3(+)IL-17(+) cells

诊断前基因分型可识别出 Treg IL-2 信号通路受损且 FOXP3(+)IL-17(+) 细胞比例升高的 1 型糖尿病患者。

Marwaha, A K; Panagiotopoulos, C; Biggs, C M; Staiger, S; Del Bel, K L; Hirschfeld, A F; Priatel, J J; Turvey, S E; Tan, R

The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling

副胱天蛋白酶 MALT1 切割 HOIL1,降低 LUBAC 的线性泛素化,从而抑制淋巴细胞 NF-κB 信号传导

Theo Klein, Shan-Yu Fung, Florian Renner, Michael A Blank, Antoine Dufour, Sohyeong Kang, Madison Bolger-Munro, Joshua M Scurll, John J Priatel, Patrick Schweigler, Samu Melkko, Michael R Gold, Rosa I Viner, Catherine H Régnier, Stuart E Turvey, Christopher M Overall

CD1d Expression and Invariant NKT Cell Responses in Herpesvirus Infections

疱疹病毒感染中CD1d表达和不变NKT细胞反应

Chung, Brian K; Priatel, John J; Tan, Rusung