日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Differential Role of Serines and Threonines in Intracellular Loop 3 and C-Terminal Tail of the Histamine H(4) Receptor in β-Arrestin and G Protein-Coupled Receptor Kinase Interaction, Internalization, and Signaling

丝氨酸和苏氨酸在组胺H(4)受体胞内环3和C端尾部中的差异性作用在β-抑制蛋白和G蛋白偶联受体激酶的相互作用、内化和信号传导中的作用

Verweij, Eléonore W E; Al Araaj, Betty; Prabhata, Wimzy R; Prihandoko, Rudi; Nijmeijer, Saskia; Tobin, Andrew B; Leurs, Rob; Vischer, Henry F

Structural insight into allosteric modulation of protease-activated receptor 2

蛋白酶激活受体 2 变构调节的结构洞察

Robert K Y Cheng, Cédric Fiez-Vandal, Oliver Schlenker, Karl Edman, Birte Aggeler, Dean G Brown, Giles A Brown, Robert M Cooke, Christoph E Dumelin, Andrew S Doré, Stefan Geschwindner, Christoph Grebner, Nils-Olov Hermansson, Ali Jazayeri, Patrik Johansson, Louis Leong, Rudi Prihandoko, Mathieu Rapp

FFA4/GPR120: Pharmacology and Therapeutic Opportunities

FFA4/GPR120:药理学和治疗机遇

Milligan, Graeme; Alvarez-Curto, Elisa; Hudson, Brian D; Prihandoko, Rudi; Tobin, Andrew B

Targeted Elimination of G Proteins and Arrestins Defines Their Specific Contributions to Both Intensity and Duration of G Protein-coupled Receptor Signaling

蛋白和抑制蛋白的靶向消除决定了它们对 G 蛋白偶联受体信号强度和持续时间的具体贡献

Elisa Alvarez-Curto, Asuka Inoue, Laura Jenkins, Sheikh Zahir Raihan, Rudi Prihandoko, Andrew B Tobin, Graeme Milligan

An Antibody Biosensor Establishes the Activation of the M1 Muscarinic Acetylcholine Receptor during Learning and Memory

抗体生物传感器可确定学习和记忆过程中M1毒蕈碱乙酰胆碱受体的激活情况

Butcher, Adrian J; Bradley, Sophie J; Prihandoko, Rudi; Brooke, Simon M; Mogg, Adrian; Bourgognon, Julie-Myrtille; Macedo-Hatch, Timothy; Edwards, Jennifer M; Bottrill, Andrew R; Challiss, R A John; Broad, Lisa M; Felder, Christian C; Tobin, Andrew B

Concomitant action of structural elements and receptor phosphorylation determines arrestin-3 interaction with the free fatty acid receptor FFA4

结构元件和受体磷酸化的协同作用决定了阻遏蛋白-3与游离脂肪酸受体FFA4的相互作用。

Butcher, Adrian J; Hudson, Brian D; Shimpukade, Bharat; Alvarez-Curto, Elisa; Prihandoko, Rudi; Ulven, Trond; Milligan, Graeme; Tobin, Andrew B

Developing chemical genetic approaches to explore G protein-coupled receptor function: validation of the use of a receptor activated solely by synthetic ligand (RASSL)

开发化学遗传学方法探索 G 蛋白偶联受体功能:验证仅由合成配体激活的受体 (RASSL) 的使用

Elisa Alvarez-Curto, Rudi Prihandoko, Christofer S Tautermann, Jurriaan M Zwier, John D Pediani, Martin J Lohse, Carsten Hoffmann, Andrew B Tobin, Graeme Milligan