日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cytomegalovirus Worsens Necrotizing Enterocolitis Severity in Mice via Increased Toll-Like Receptor 4 Signaling.

巨细胞病毒通过增强 Toll 样受体 4 信号传导加重小鼠坏死性小肠结肠炎的严重程度

Scheese Daniel, Lu Peng, Moore Hannah, Tsuboi Koichi, Tragesser Cody, Duess Johannes, Raouf Zachariah, Sampah Maame F, Klerk Daphne, El Baassiri Mahmoud, Jang Hee-Seong, Williams-McLeod Sierra, Ishiyama Asuka, Steinway Steve N, Wang Sanxia, Wang Menghan, Prindle Thomas Jr, Fulton William B, Sodhi Chhinder P, Hackam David J

Toll Like Receptor 4 Mediated Lymphocyte Imbalance Induces Nec-Induced Lung Injury

Toll样受体4介导的淋巴细胞失衡诱导坏死性筋膜炎病毒(NEC)引起的肺损伤

Jia, Hongpeng; Sodhi, Chhinder P; Yamaguchi, Yukihiro; Lu, Peng; Ladd, Mitchell R; Werts, Adam; Fulton, William B; Wang, Sanxia; Prindle, Thomas Jr; Hackam, David J

Cognitive impairments induced by necrotizing enterocolitis can be prevented by inhibiting microglial activation in mouse brain

抑制小鼠脑内小胶质细胞活化可以预防坏死性小肠结肠炎引起的认知障碍

Niño, Diego F; Zhou, Qinjie; Yamaguchi, Yukihiro; Martin, Laura Y; Wang, Sanxia; Fulton, William B; Jia, Hongpeng; Lu, Peng; Prindle, Thomas Jr; Zhang, Fan; Crawford, Joshua; Hou, Zhipeng; Mori, Susumu; Chen, Liam L; Guajardo, Andrew; Fatemi, Ali; Pletnikov, Mikhail; Kannan, Rangaramanujam M; Kannan, Sujatha; Sodhi, Chhinder P; Hackam, David J

Synthesis of anti-inflammatory α-and β-linked acetamidopyranosides as inhibitors of toll-like receptor 4 (TLR4)

合成抗炎α-和β-连接的乙酰氨基吡喃糖苷作为Toll样受体4(TLR4)抑制剂

Wipf, Peter; Eyer, Benjamin R; Yamaguchi, Yukihiro; Zhang, Feng; Neal, Matthew D; Sodhi, Chhinder P; Good, Misty; Branca, Maria; Prindle, Thomas Jr; Lu, Peng; Brodsky, Jeffrey L; Hackam, David J

Toll-like receptor 4-mediated endoplasmic reticulum stress in intestinal crypts induces necrotizing enterocolitis

Toll样受体4介导的肠隐窝内质网应激可诱发坏死性小肠结肠炎

Afrazi, Amin; Branca, Maria F; Sodhi, Chhinder P; Good, Misty; Yamaguchi, Yukihiro; Egan, Charlotte E; Lu, Peng; Jia, Hongpeng; Shaffiey, Shahab; Lin, Joyce; Ma, Congrong; Vincent, Garrett; Prindle, Thomas Jr; Weyandt, Samantha; Neal, Matthew D; Ozolek, John A; Wiersch, John; Tschurtschenthaler, Markus; Shiota, Chiyo; Gittes, George K; Billiar, Timothy R; Mollen, Kevin; Kaser, Arthur; Blumberg, Richard; Hackam, David J

Intestinal epithelial Toll-like receptor 4 regulates goblet cell development and is required for necrotizing enterocolitis in mice

肠道上皮细胞 Toll 样受体 4 调控杯状细胞发育,并且是小鼠坏死性小肠结肠炎所必需的。

Sodhi, Chhinder P; Neal, Matthew D; Siggers, Richard; Sho, Shonan; Ma, Congrong; Branca, Maria F; Prindle, Thomas Jr; Russo, Anthony M; Afrazi, Amin; Good, Misty; Brower-Sinning, Rachel; Firek, Brian; Morowitz, Michael J; Ozolek, John A; Gittes, George K; Billiar, Timothy R; Hackam, David J

Toll-like receptor 4 is expressed on intestinal stem cells and regulates their proliferation and apoptosis via the p53 up-regulated modulator of apoptosis

Toll样受体4在肠道干细胞上表达,并通过p53上调的凋亡调节因子来调控其增殖和凋亡。

Neal, Matthew D; Sodhi, Chhinder P; Jia, Hongpeng; Dyer, Mitchell; Egan, Charlotte E; Yazji, Ibrahim; Good, Misty; Afrazi, Amin; Marino, Ryan; Slagle, Dennis; Ma, Congrong; Branca, Maria F; Prindle, Thomas Jr; Grant, Zachary; Ozolek, John; Hackam, David J

Nucleotide-binding oligomerization domain-2 inhibits toll-like receptor-4 signaling in the intestinal epithelium

核苷酸结合寡聚化结构域2抑制肠上皮细胞中的Toll样受体4信号传导

Richardson, Ward M; Sodhi, Chhinder P; Russo, Anthony; Siggers, Richard H; Afrazi, Amin; Gribar, Steven C; Neal, Matthew D; Dai, Shipan; Prindle, Thomas Jr; Branca, Maria; Ma, Congrong; Ozolek, John; Hackam, David J