Lead optimization of a 4-aminopyridine benzamide scaffold to identify potent, selective, and orally bioavailable TYK2 inhibitors
4-氨基吡啶苯甲酰胺支架的先导优化，以鉴定有效、选择性且可口服生物利用的 TYK2 抑制剂
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/jm400266t
Jun Liang, Anne van Abbema, Mercedesz Balazs, Kathy Barrett, Leo Berezhkovsky, Wade Blair, Christine Chang, Donnie Delarosa, Jason DeVoss, Jim Driscoll, Charles Eigenbrot, Nico Ghilardi, Paul Gibbons, Jason Halladay, Adam Johnson, Pawan Bir Kohli, Yingjie Lai, Yanzhou Liu, Joseph Lyssikatos, Priscil
