Colorectal cancer cells with the BRAF(V600E) mutation are addicted to the ERK1/2 pathway for growth factor-independent survival and repression of BIM.
具有 BRAF(V600E) 突变的结直肠癌细胞依赖 ERK1/2 通路进行不依赖生长因子的生存和 BIM 的抑制
期刊:Oncogene
影响因子:7.3
doi:10.1038/onc.2008.335
Wickenden J A, Jin H, Johnson M, Gillings A S, Newson C, Austin M, Chell S D, Balmanno K, Pritchard C A, Cook S J
