日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Actin-binding compounds, previously discovered by FRET-based high-throughput screening, differentially affect skeletal and cardiac muscle.

肌动蛋白结合化合物,此前通过基于 FRET 的高通量筛选发现,对骨骼肌和心肌的影响不同

Guhathakurta Piyali, Phung Lien A, Prochniewicz Ewa, Lichtenberger Sarah, Wilson Anna, Thomas David D

Actin-Myosin Interaction: Structure, Function and Drug Discovery

肌动蛋白-肌球蛋白相互作用:结构、功能和药物发现

Guhathakurta, Piyali; Prochniewicz, Ewa; Thomas, David D

A Cardiomyopathy Mutation in the Myosin Essential Light Chain Alters Actomyosin Structure

肌球蛋白必需轻链的突变导致心肌病,并改变肌动球蛋白结构。

Guhathakurta, Piyali; Prochniewicz, Ewa; Roopnarine, Osha; Rohde, John A; Thomas, David D

Amplitude of the actomyosin power stroke depends strongly on the isoform of the myosin essential light chain

肌动球蛋白动力冲程的幅度强烈依赖于肌球蛋白必需轻链的亚型。

Guhathakurta, Piyali; Prochniewicz, Ewa; Thomas, David D

Cardiac myosin binding protein-C restricts intrafilament torsional dynamics of actin in a phosphorylation-dependent manner

心肌肌球蛋白结合蛋白-C以磷酸化依赖的方式限制肌动蛋白丝内的扭转动力学。

Colson, Brett A; Rybakova, Inna N; Prochniewicz, Ewa; Moss, Richard L; Thomas, David D

Allosteric communication in Dictyostelium myosin II

盘基网柄菌肌球蛋白 II 中的变构通讯

Guhathakurta, Piyali; Prochniewicz, Ewa; Muretta, Joseph M; Titus, Margaret A; Thomas, David D

Functional, structural, and chemical changes in myosin associated with hydrogen peroxide treatment of skeletal muscle fibers

过氧化氢处理骨骼肌纤维引起的肌球蛋白功能、结构和化学变化

Prochniewicz, Ewa; Lowe, Dawn A; Spakowicz, Daniel J; Higgins, LeeAnn; O'Conor, Kate; Thompson, LaDora V; Ferrington, Deborah A; Thomas, David D

Changes in actin structural transitions associated with oxidative inhibition of muscle contraction

与肌肉收缩氧化抑制相关的肌动蛋白结构转变的变化

Prochniewicz, Ewa; Spakowicz, Daniel; Thomas, David D

Age-related decline in actomyosin structure and function

与年龄相关的肌动球蛋白结构和功能的衰退

Prochniewicz, Ewa; Thompson, LaDora V; Thomas, David D

Changes in actin and myosin structural dynamics due to their weak and strong interactions

肌动蛋白和肌球蛋白由于弱相互作用和强相互作用而引起的结构动力学变化。

Thomas, David D; Prochniewicz, Ewa; Roopnarine, Osha