Combination of 5-fluorouracil and N1,N11-diethylnorspermine markedly activates spermidine/spermine N1-acetyltransferase expression, depletes polyamines, and synergistically induces apoptosis in colon carcinoma cells.

5-氟尿嘧啶和N1,N11-二乙基去甲精胺的组合显著激活亚精胺/精胺N1-乙酰转移酶的表达，消耗多胺，并协同诱导结肠癌细胞凋亡