Particle uptake by macrophages triggers bifurcated transcriptional pathways that differentially regulate inflammation and lysosomal gene expression.
巨噬细胞对颗粒的摄取会触发分叉的转录通路,从而差异性地调节炎症和溶酶体基因表达
期刊:Immunity
影响因子:26.3
doi:10.1016/j.immuni.2025.02.023
Cobo Isidoro, Murillo-Saich Jessica, Alishala Mohnish, Calderon Stephen, Coras Roxana, Hemming Benjamin, Inkum Faith, Rosas Fiorella, Takei Riku, Spann Nathan, Prohaska Thomas A, Alabarse Paulo V G, Jeong Se-Jin, Nickl Christian K, Cheng Anyan, Li Benjamin, Vogel Andrea, Weichhart Thomas, Fuster José J, Le Thomas, Bradstreet Tara R, Webber Ashlee M, Edelson Brian T, Razani Babak, Ebert Benjamin L, Taneja Reshma, Terkeltaub Robert, Bryan Ru Liu, Guma Monica, Glass Christopher K