日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Particle uptake by macrophages triggers bifurcated transcriptional pathways that differentially regulate inflammation and lysosomal gene expression.

巨噬细胞对颗粒的摄取会触发分叉的转录通路,从而差异性地调节炎症和溶酶体基因表达

Cobo Isidoro, Murillo-Saich Jessica, Alishala Mohnish, Calderon Stephen, Coras Roxana, Hemming Benjamin, Inkum Faith, Rosas Fiorella, Takei Riku, Spann Nathan, Prohaska Thomas A, Alabarse Paulo V G, Jeong Se-Jin, Nickl Christian K, Cheng Anyan, Li Benjamin, Vogel Andrea, Weichhart Thomas, Fuster José J, Le Thomas, Bradstreet Tara R, Webber Ashlee M, Edelson Brian T, Razani Babak, Ebert Benjamin L, Taneja Reshma, Terkeltaub Robert, Bryan Ru Liu, Guma Monica, Glass Christopher K

Design and rationale of the CORE-TIMI 72a and CORE2-TIMI 72b trials of olezarsen in patients with severe hypertriglyceridemia

奥利沙坦治疗重度高甘油三酯血症患者的 CORE-TIMI 72a 和 CORE2-TIMI 72b 试验的设计和原理

Marston, Nicholas A; Bergmark, Brian A; Alexander, Veronica J; Karwatowska-Prokopczuk, Ewa; Kang, Yu Mi; Moura, Filipe A; Prohaska, Thomas A; Zimerman, Andre; Zhang, Shuanglu; Murphy, Sabina A; Tsimikas, Sotirios; Giugliano, Robert P; Sabatine, Marc S

Olezarsen in patients with hypertriglyceridemia at high cardiovascular risk: Rationale and design of the Essence-TIMI 73b trial

奥拉扎森用于伴有高心血管风险的高甘油三酯血症患者:Essence-TIMI 73b试验的原理和设计

Bergmark, Brian A; Marston, Nicholas A; Prohaska, Thomas A; Alexander, Veronica J; Zimerman, Andre; Moura, Filipe A; Kang, Yu Mi; Murphy, Sabina A; Zhang, Shuanglu; Lu, Michael T; Karwatowska-Prokopczuk, Ewa; Tsimikas, Sotirios; Giugliano, Robert P; Sabatine, Marc S

B-1b Cells Have Unique Functional Traits Compared to B-1a Cells at Homeostasis and in Aged Hyperlipidemic Mice With Atherosclerosis

在稳态和患有动脉粥样硬化的老年高脂血症小鼠中,B-1b 细胞与 B-1a 细胞相比具有独特的功能特征。

Srikakulapu, Prasad; Pattarabanjird, Tanyaporn; Upadhye, Aditi; Bontha, Sai Vineela; Osinski, Victoria; Marshall, Melissa A; Garmey, James; Deroissart, Justine; Prohaska, Thomas A; Witztum, Joseph L; Binder, Christoph J; Holodick, Nichol E; Rothstein, Thomas L; McNamara, Coleen A

Massively Parallel Sequencing of Peritoneal and Splenic B Cell Repertoires Highlights Unique Properties of B-1 Cell Antibodies

腹膜和脾脏B细胞库的大规模并行测序揭示了B-1细胞抗体的独特特性

Prohaska, Thomas A; Que, Xuchu; Diehl, Cody J; Hendrikx, Sabrina; Chang, Max W; Jepsen, Kristen; Glass, Christopher K; Benner, Christopher; Witztum, Joseph L

Protective Role for B-1b B Cells and IgM in Obesity-Associated Inflammation, Glucose Intolerance, and Insulin Resistance

B-1b B 细胞和 IgM 在肥胖相关炎症、葡萄糖耐受不良和胰岛素抵抗中的保护作用

Harmon, Daniel B; Srikakulapu, Prasad; Kaplan, Jennifer L; Oldham, Stephanie N; McSkimming, Chantel; Garmey, James C; Perry, Heather M; Kirby, Jennifer L; Prohaska, Thomas A; Gonen, Ayelet; Hallowell, Peter; Schirmer, Bruce; Tsimikas, Sotirios; Taylor, Angela M; Witztum, Joseph L; McNamara, Coleen A