日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The cytoskeleton contributes to abnormal genome-lamina interactions in LMNA-deficient cardiomyocytes.

细胞骨架导致 LMNA 缺陷型心肌细胞中基因组-核纤层相互作用异常。

Shen Kaitlyn M, Shields Emily J, Barka Vasia, Karnay Ashley, Kurzlechner Leonie M, Yang Jennifer D, Wang Qiaohong, Lee Benjamin W, Suay-Corredera Carmen, Nguyen Son C, Joyce Eric F, Margulies Kenneth B, Prosser Benjamin L, Shah Parisha P, Jain Rajan

Pathogenic KIF1A variants differentially disrupt axonal trafficking and impede synaptic development

致病性KIF1A变异体对轴突运输的干扰程度不同,并会阻碍突触发育。

Aiken, Jayne; Borland, Carris; Marotta, Nicolas; Prosser, Benjamin L; Holzbaur, Erika L F

Active transport of tRNAs facilitates distributed protein synthesis.

tRNA的主动运输促进了蛋白质的分布式合成。

Petrosino Jennifer M, Courelli Vasiliki, Uchida Keita, Bond Charles, Cooperman Barry, Bogush Alexey, Lakadamyali Melike, Prosser Benjamin L

Familial SYNGAP1 variants define the boundaries of a complex neurodevelopmental disorder with epilepsy

家族性SYNGAP1变异定义了一种伴有癫痫的复杂神经发育障碍的边界。

Harrison, Alicia G; Magielski, Jan H; McSalley, Ian; Ganesan, Shiva; Prentice, Anna J; Cunningham, Kristin G; Pierce, Samuel R; Boland, Michael J; Prosser, Benjamin L; Helbig, Ingo; McKee, Jillian L

Clinical signatures of SYNGAP1-related disorders through data integration

通过数据整合分析SYNGAP1相关疾病的临床特征

McKee, Jillian L; Magielski, Jan H; Xian, Julie; Cohen, Stacey; Toib, Jonathan; Harrison, Alicia; Chen, Chen; Kim, Dan; Rathod, Aakash; Brimble, Elise; Fitter, Nasha; Graglia, J Michael; Helde, Kathryn A; McKeown Ruggiero, Sarah; Boland, Michael J; Prosser, Benjamin L; Sederman, Rob; Helbig, Ingo

Ultrastructure analysis of mitochondria, lipid droplet and sarcoplasmic reticulum apposition in human heart failure

人类心力衰竭中线粒体、脂滴和肌浆网排列的超微结构分析

Latchman, Nadina R; Stevens, Tyler L; Bedi, Kenneth C; Prosser, Benjamin L; Margulies, Kenneth B; Elrod, John W

CRISPR-mediated transcriptional activation as a mutation-independent therapeutic strategy for SYNGAP1-related intellectual disability

CRISPR介导的转录激活作为一种不依赖于突变的SYNGAP1相关智力障碍治疗策略

Sichlinger, Laura; Reilly, Molly B; Arora, Sakshi; Zhang, Shuo; Marotta, Nicolas; Rodríguez-Acevedo, Kiara L; Hooks, Marisol; Czarnecki, Kyle S; Winter, Julia J; Waxman, Elisa A; Dungan, Lea V; Hong, Ingie; Araki, Yoichi; Johnson, Richard; Huganir, Richard L; Pavani, Giulia; French, Deborah L; Davidson, Beverly L; Prosser, Benjamin L; Heller, Elizabeth A

Integrated Stress Response Potentiates Ponatinib-Induced Cardiotoxicity

整合应激反应增强帕纳替尼诱导的心脏毒性

Yan, Gege; Han, Zhenbo; Kwon, Youjeong; Jousma, Jordan; Nukala, Sarath Babu; Prosser, Benjamin L; Du, Xiaoping; Pinho, Sandra; Ong, Sang-Bing; Lee, Won Hee; Ong, Sang-Ging

Truncated titin protein in dilated cardiomyopathy incorporates into the sarcomere and transmits force

扩张型心肌病中截短的肌联蛋白整合到肌节中并传递力量。

McAfee, Quentin; Caporizzo, Matthew A; Uchida, Keita; Bedi, Kenneth C Jr; Margulies, Kenneth B; Arany, Zolt; Prosser, Benjamin L

An Unbiased Screen Identified the Hsp70-BAG3 Complex as a Regulator of Myosin-Binding Protein C3

一项无偏筛选鉴定出 Hsp70-BAG3 复合物是肌球蛋白结合蛋白 C3 的调节因子

Thompson, Andrea D; Wagner, Marcus J; Rodriguez, Juliani; Malhotra, Alok; Vander Roest, Steve; Lilienthal, Ulla; Shao, Hao; Vignesh, Mathav; Weber, Keely; Yob, Jaime M; Prosser, Benjamin L; Helms, Adam S; Gestwicki, Jason E; Ginsburg, David; Day, Sharlene M