Combinatory differentiation of human induced pluripotent stem cells generates functional thymic epithelium driving dendritic cell and CD4/CD8 T cell development
人诱导多能干细胞的组合分化可生成功能性胸腺上皮,进而驱动树突状细胞和CD4/CD8 T细胞的发育。
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-68675-y
Provin, Nathan; d'Arco, Manon; Le Bozec, Antoine; Kervagoret, Erwan; Bruneau, Alexandre; Brusselle, Lucas; Fourgeux, Cynthia; Poschmann, Jeremie; Hulin, Philippe; Maminirina, Pierre; Baron, Olivier; Saulquin, Xavier; Guillonneau, Carole; David, Laurent; Giraud, Matthieu
发育与干细胞
T细胞
树突状细胞
CD8
T细胞
CD4
干细胞
细胞生物学
树突状细胞
免疫/内分泌