日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Corrigendum to "Conformational Transformation and Selection of Synthetic Prion Strains" [J. Mol. Biol. 413(3) (2011) 527-542]

对“构象转变和合成朊病毒株的选择”的更正[J. Mol. Biol. 413(3) (2011) 527-542]

Ghaemmaghami, Sina; Watts, Joel C; Nguyen, Hoang-Oanh; Hayashi, Shigenari; DeArmond, Stephen J; Prusiner, Stanley B

Cryo-EM structure of a novel α-synuclein filament subtype from multiple system atrophy

多系统萎缩症中一种新型α-突触核蛋白丝亚型的冷冻电镜结构

Yan, Nicholas L; Candido, Francisco; Tse, Eric; Melo, Arthur A; Prusiner, Stanley B; Mordes, Daniel A; Southworth, Daniel R; Paras, Nick A; Merz, Gregory E

Severe neurodegeneration in brains of transgenic rats producing human tau prions

产生人类 tau 朊病毒的转基因大鼠大脑发生严重神经退化

Jacob Ayers #, T Peter Lopez #, Ian T Steele, Abby Oehler, Rigo Roman-Albarran, Elisa Cleveland, Alex Chong, George A Carlson, Carlo Condello, Stanley B Prusiner

Cryo-EM structures reveal tau filaments from Down syndrome adopt Alzheimer's disease fold

低温电子显微镜结构揭示唐氏综合症的 tau 蛋白丝呈现阿尔茨海默病的折叠

Ujjayini Ghosh #, Eric Tse #, Hyunjun Yang, Marie Shi, Christoffer D Caro, Feng Wang, Gregory E Merz, Stanley B Prusiner, Daniel R Southworth, Carlo Condello

Viroids, Satellite RNAs and Prions: Folding of Nucleic Acids and Misfolding of Proteins

类病毒、卫星RNA和朊病毒:核酸的折叠和蛋白质的错误折叠

Steger, Gerhard; Riesner, Detlev; Prusiner, Stanley B

Cryo-EM Structures Reveal Tau Filaments from Down Syndrome Adopt Alzheimer's Disease Fold

冷冻电镜结构揭示唐氏综合征患者的tau蛋白丝会折叠成阿尔茨海默病患者的折叠结构。

Ghosh, Ujjayini; Tse, Eric; Yang, Hyunjun; Shi, Marie; Carlo, Christoffer D; Wang, Feng; Merz, Gregory E; Prusiner, Stanley B; Southworth, Daniel R; Condello, Carlo

Stacked binding of a PET ligand to Alzheimer's tau paired helical filaments

PET配体与阿尔茨海默病tau蛋白成对螺旋丝的堆叠结合

Merz, Gregory E; Chalkley, Matthew J; Tan, Sophia K; Tse, Eric; Lee, Joanne; Prusiner, Stanley B; Paras, Nick A; DeGrado, William F; Southworth, Daniel R

Guam ALS-PDC is a distinct double-prion disorder featuring both tau and Aβ prions

关岛 ALS-PDC 是一种独特的双朊病毒疾病,特征是 tau 和 Aβ 朊病毒

Carlo Condello, Jacob I Ayers, Clifton L Dalgard, M Madhy Garcia Garcia, Brianna M Rivera, William W Seeley, Daniel P Perl, Stanley B Prusiner

Trans-channel fluorescence learning improves high-content screening for Alzheimer's disease therapeutics

跨通道荧光学习改善阿尔茨海默病治疗的高内涵筛选

Daniel R Wong, Jay Conrad, Noah Johnson, Jacob Ayers, Annelies Laeremans, Joanne C Lee, Jisoo Lee, Stanley B Prusiner, Sourav Bandyopadhyay, Atul J Butte, Nick A Paras, Michael J Keiser

Multiple system atrophy prions transmit neurological disease to mice expressing wild-type human α-synuclein

多系统萎缩朊病毒将神经系统疾病传播给表达野生型人类 α-突触核蛋白的小鼠

Sara A M Holec, Jisoo Lee, Abby Oehler, Felicia K Ooi, Daniel A Mordes, Steven H Olson, Stanley B Prusiner, Amanda L Woerman