日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

APOE isoform-associated tau oligomer polymorphs differ in synaptotoxicity and seeding activity

APOE同工型相关的tau寡聚体多晶型在突触毒性和播散活性方面存在差异

Moreno, Naomi; Shchankin, Nikita; Fung, Leiana; Puangmalai, Nicha; Bhatt, Nemil; Haque, Md Anzarul; Zhao, Yingxin; Keene, C Dirk; Limon, Agenor; Kayed, Rakez

Pathogenic oligomeric Tau alters neuronal RNA processes through the formation of nuclear heteromeric amyloids with RNA-binding protein Musashi1

致病性寡聚体Tau蛋白通过与RNA结合蛋白Musashi1形成核异聚体淀粉样蛋白,从而改变神经元RNA过程。

Nicha Puangmalai ,Abbigael E Aday ,Madison Samples ,Nemil Bhatt ,Filippa Lo Cascio ,Michela Marcatti ,Suhyeorn J Park ,Leiana Fung ,Cynthia Jerez ,Luiz O Penalva ,Yingxin Zhao ,Haiping Hao ,Doreen Lugano ,Rakez Kayed ,Mauro Montalbano

Brain-derived tau oligomer polymorphs: distinct aggregations, stability profiles, and biological activities.

脑源性 tau 寡聚体多晶型:不同的聚集体、稳定性特征和生物活性

Lo Cascio Filippa, Park Suhyeorn, Sengupta Urmi, Puangmalai Nicha, Bhatt Nemil, Shchankin Nikita, Jerez Cynthia, Moreno Naomi, Bittar Alice, Xavier Rhea, Zhao Yingxin, Wang Cankun, Fu Hongjun, Ma Qin, Montalbano Mauro, Kayed Rakez

Characterization of conformation-specific antibodies TOMA-1 and TTCM-1 for recombinant tau monomer and amplified brain derived tau oligomer

对重组tau单体和扩增的脑源性tau寡聚体的构象特异性抗体TOMA-1和TTCM-1进行表征

Haque, Md Anzarul; Montalbano, Mauro; Khan, Sheeza; Puangmalai, Nicha; Bhatt, Nemil; Shchankin, Nikita; Jerez, Cynthia; Kayed, Rakez

C-Terminal Modification Contributes the Antibacterial Activity of a Cecropin-like Region of Heteroscorpine-1 from Scorpion Venom

蝎毒异蝎素-1中类似天蚕素区域的C端修饰赋予其抗菌活性

Saengkun, Yutthakan; Klamrak, Anuwatchakij; Janpan, Piyapon; Rahman, Shaikh Shahinur; Erviana, Rima; Puangmalai, Nawan; Jangpromma, Nisachon; Daduang, Jureerut; Daduang, Sakda; Areemit, Jringjai

C9orf72-associated dipeptide protein repeats form A11-positive oligomers in amyotrophic lateral sclerosis and frontotemporal dementia

C9orf72相关二肽蛋白重复序列在肌萎缩侧索硬化症和额颞叶痴呆中形成A11阳性寡聚体

Bhatt, Nemil; Puangmalai, Nicha; Sengupta, Urmi; Jerez, Cynthia; Kidd, Madison; Gandhi, Shailee; Kayed, Rakez

Toxic Interplay Between Small Dipeptide Protein Repeats and Tau in Tauopathies

小二肽蛋白重复序列与Tau蛋白在Tau蛋白病中的毒性相互作用

Havelaar, Arie H; van Rosse, Floor; Bucura, Catalin; Toetenel, Milou A; Haagsma, Juanita A; Kurowicka, Dorota; Heesterbeek, J Hans A P; Speybroeck, Niko; Langelaar, Merel F M; van der Giessen, Johanna W B; Cooke, Roger M; Braks, Marieta A H; Bhatt, Nemil; Puangmalai, Nicha; Jerez, Cynthia; Shchankin, Nikita; Kayed, Rakez

Polymorphic Alpha-Synuclein Oligomers: Characterization and Differential Detection with Novel Corresponding Antibodies

多态性 α-突触核蛋白寡聚体:用新型相应抗体进行表征和差异检测

Kenya Moore, Urmi Sengupta, Nicha Puangmalai, Nemil Bhatt, Rakez Kayed

Lysine 63-linked ubiquitination of tau oligomers contributes to the pathogenesis of Alzheimer's disease

tau 寡聚体的赖氨酸 63 连接泛素化促进阿尔茨海默病的发病机制

Nicha Puangmalai, Urmi Sengupta, Nemil Bhatt, Sagar Gaikwad, Mauro Montalbano, Arijit Bhuyan, Stephanie Garcia, Salome McAllen, Minal Sonawane, Cynthia Jerez, Yingxin Zhao, Rakez Kayed

Distinct neurotoxic TDP-43 fibril polymorphs are generated by heterotypic interactions with α-Synuclein

通过与 α-突触核蛋白的异型相互作用产生独特的神经毒性 TDP-43 原纤维多形体

Shailendra Dhakal, Alicia S Robang, Nemil Bhatt, Nicha Puangmalai, Leiana Fung, Rakez Kayed, Anant K Paravastu, Vijayaraghavan Rangachari