日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Patient-derived xenograft models of Fanconi anemia-associated head and neck cancer identify personalized therapeutic strategies

利用范可尼贫血相关头颈癌的患者来源异种移植模型,可以确定个体化的治疗策略。

Grandis, Jennifer R; Li, Hua; Harrison, Benjamin A; Webster, Andrew Lh; Pucilowska, Joanna; Nguyen, Austin; Lee, Jinho; Mills, Gordon B; Gencel-Augusto, Jovanka; Zeng, Yan; Long, Steven R; Kim, Mi-Ok; Lee, Rex H; Kutler, David I; Scognamiglio, Theresa; Brandwein-Weber, Margaret; Urken, Mark; Khodos, Inna; de Stanchina, Elisa; Lin, Yu-Chien; Donovan, Frank X; Chandrasekharappa, Settara C; Jung, Moonjung; Sanders, Mathijs A; Smogorzewska, Agata; Johnson, Daniel E

Bacterial colonization of tumors drives immune activation and checkpoint blockade efficacy

肿瘤的细菌定植会激活免疫反应并增强免疫检查点阻断的疗效。

Rolig, Annah S; Ziglari, Tahereh; McGee, Grace Helen; Kasiewicz, Melissa J; Kolbaba, Kenna; Simons, Noah D; Pucilowska, Joanna; Sfanos, Karen; Redmond, William L

A phase Ib trial of pembrolizumab plus paclitaxel or flat-dose capecitabine in 1st/2nd line metastatic triple-negative breast cancer

帕博利珠单抗联合紫杉醇或固定剂量卡培他滨治疗一线/二线转移性三阴性乳腺癌的 Ib 期临床试验

David B Page, Joanna Pucilowska, Brie Chun, Isaac Kim, Katherine Sanchez, Nicole Moxon, Staci Mellinger, Yaping Wu, Yoshinobu Koguchi, Valerie Conrad, William L Redmond, Maritza Martel, Zhaoyu Sun, Mary B Campbell, Alison Conlin, Anupama Acheson, Reva Basho, Philomena McAndrew, Mary El-Masry, Doroth

Changes in T-cell subsets and clonal repertoire during chemoimmunotherapy with pembrolizumab and paclitaxel or capecitabine for metastatic triple-negative breast cancer

转移性三阴性乳腺癌接受派姆单抗和紫杉醇或卡培他滨化学免疫治疗期间 T 细胞亚群和克隆库的变化

Brie Chun, Joanna Pucilowska, ShuChing Chang, Isaac Kim, Benjamin Nikitin, Yoshinobu Koguchi, William L Redmond, Brady Bernard, Venkatesh Rajamanickam, Nathan Polaske, Paul A Fields, Valerie Conrad, Mark Schmidt, Walter J Urba, Alison K Conlin, Heather L McArthur, David B Page

Germinal center reactions in tertiary lymphoid structures associate with neoantigen burden, humoral immunity and long-term survivorship in pancreatic cancer

三级淋巴结构中的生发中心反应与胰腺癌的新抗原负担、体液免疫和长期存活率相关

Andrew J Gunderson, Venkatesh Rajamanickam, Cynthia Bui, Brady Bernard, Joanna Pucilowska, Carmen Ballesteros-Merino, Mark Schmidt, Kayla McCarty, Michaela Philips, Brian Piening, Christopher Dubay, Terry Medler, Phillipa Newell, Paul Hansen, Eric Tran, Ephraim Tang, Carlo Bifulco, Marka Crittenden,

Chronic impairment of ERK signaling in glutamatergic neurons of the forebrain does not affect spatial memory retention and LTP in the same manner as acute blockade of the ERK pathway

前脑谷氨酸能神经元中 ERK 信号的慢性损伤不会像 ERK 通路的急性阻断那样影响空间记忆保持和 LTP

Joseph Vithayathil, Joanna Pucilowska, David Friel, Gary E Landreth

The 16p11.2 deletion mouse model of autism exhibits altered cortical progenitor proliferation and brain cytoarchitecture linked to the ERK MAPK pathway

16p11.2 缺失的自闭症小鼠模型表现出与 ERK MAPK 通路相关的皮质祖细胞增殖和脑细胞结构的改变

Joanna Pucilowska, Joseph Vithayathil, Emmanuel J Tavares, Caitlin Kelly, J Colleen Karlo, Gary E Landreth

Dentate Gyrus Development Requires ERK Activity to Maintain Progenitor Population and MAPK Pathway Feedback Regulation

齿状回发育需要ERK活性来维持祖细胞群和MAPK通路反馈调节。

Vithayathil, Joseph; Pucilowska, Joanna; Goodnough, L Henry; Atit, Radhika P; Landreth, Gary E

Disrupted ERK signaling during cortical development leads to abnormal progenitor proliferation, neuronal and network excitability and behavior, modeling human neuro-cardio-facial-cutaneous and related syndromes

皮质发育过程中 ERK 信号传导中断会导致祖细胞增殖异常、神经元和网络兴奋性和行为异常,模拟人类神经心脏面部皮肤和相关综合征

Joanna Pucilowska, Pavel A Puzerey, J Colleen Karlo, Roberto F Galán, Gary E Landreth

Expression of insulin-like growth factor I by activated hepatic stellate cells reduces fibrogenesis and enhances regeneration after liver injury

活化的肝星状细胞表达胰岛素样生长因子I可减少纤维化并促进肝损伤后的再生。

Sanz, S; Pucilowska, J B; Liu, S; Rodríguez-Ortigosa, C M; Lund, P K; Brenner, D A; Fuller, C R; Simmons, J G; Pardo, A; Martínez-Chantar, M-L; Fagin, J A; Prieto, J