日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Supporting respiratory epithelia and lowering inflammation to effectively treat common cold symptoms: A randomized controlled trial

支持呼吸道上皮并降低炎症以有效治疗普通感冒症状:一项随机对照试验

Pugach, Pavel; Sadeghi-Latefi, Nazlie

The Glycan Hole Area of HIV-1 Envelope Trimers Contributes Prominently to the Induction of Autologous Neutralization

HIV-1包膜三聚体的聚糖孔区域对自体中和的诱导起着显著作用

Schorcht, Anna; Cottrell, Christopher A; Pugach, Pavel; Ringe, Rajesh P; Han, Alvin X; Allen, Joel D; van den Kerkhof, Tom L G M; Seabright, Gemma E; Schermer, Edith E; Ketas, Thomas J; Burger, Judith A; van Schooten, Jelle; LaBranche, Celia C; Ozorowski, Gabriel; de Val, Natalia; Bader, Daniel L V; Schuitemaker, Hanneke; Russell, Colin A; Montefiori, David C; van Gils, Marit J; Crispin, Max; Klasse, P J; Ward, Andrew B; Moore, John P; Sanders, Rogier W

A novel anti-inflammatory treatment for bradykinin-induced sore throat or pharyngitis

一种治疗缓激肽诱发咽喉痛或咽炎的新型抗炎疗法

Leyva-Grado, Victor; Pugach, Pavel; Sadeghi-Latefi, Nazlie

Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide

捕捉HIV-1包膜糖蛋白融合肽的固有结构动力学

Kumar, Sonu; Sarkar, Anita; Pugach, Pavel; Sanders, Rogier W; Moore, John P; Ward, Andrew B; Wilson, Ian A

Closing and Opening Holes in the Glycan Shield of HIV-1 Envelope Glycoprotein SOSIP Trimers Can Redirect the Neutralizing Antibody Response to the Newly Unmasked Epitopes

HIV-1包膜糖蛋白SOSIP三聚体糖链屏障的孔洞闭合和打开可将中和抗体反应重定向至新暴露的表位

Ringe, Rajesh P; Pugach, Pavel; Cottrell, Christopher A; LaBranche, Celia C; Seabright, Gemma E; Ketas, Thomas J; Ozorowski, Gabriel; Kumar, Sonu; Schorcht, Anna; van Gils, Marit J; Crispin, Max; Montefiori, David C; Wilson, Ian A; Ward, Andrew B; Sanders, Rogier W; Klasse, P J; Moore, John P

Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques.

HIV-1包膜糖蛋白BG505 SOSIP三聚体在兔和猕猴中诱导的中和抗体表位

Klasse P J, Ketas Thomas J, Cottrell Christopher A, Ozorowski Gabriel, Debnath Gargi, Camara Diawoye, Francomano Erik, Pugach Pavel, Ringe Rajesh P, LaBranche Celia C, van Gils Marit J, Bricault Christine A, Barouch Dan H, Crotty Shane, Silvestri Guido, Kasturi Sudhir, Pulendran Bali, Wilson Ian A, Montefiori David C, Sanders Rogier W, Ward Andrew B, Moore John P

Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike

HIV-1包膜刺突蛋白的开放和封闭结构揭示了其变构性和可塑性。

Ozorowski, Gabriel; Pallesen, Jesper; de Val, Natalia; Lyumkis, Dmitry; Cottrell, Christopher A; Torres, Jonathan L; Copps, Jeffrey; Stanfield, Robyn L; Cupo, Albert; Pugach, Pavel; Moore, John P; Wilson, Ian A; Ward, Andrew B

Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization

通过超稳定化提高天然样 HIV-1 包膜三聚体的免疫原性

Torrents de la Peña, Alba; Julien, Jean-Philippe; de Taeye, Steven W; Garces, Fernando; Guttman, Miklos; Ozorowski, Gabriel; Pritchard, Laura K; Behrens, Anna-Janina; Go, Eden P; Burger, Judith A; Schermer, Edith E; Sliepen, Kwinten; Ketas, Thomas J; Pugach, Pavel; Yasmeen, Anila; Cottrell, Christopher A; Torres, Jonathan L; Vavourakis, Charlotte D; van Gils, Marit J; LaBranche, Celia; Montefiori, David C; Desaire, Heather; Crispin, Max; Klasse, Per Johan; Lee, Kelly K; Moore, John P; Ward, Andrew B; Wilson, Ian A; Sanders, Rogier W

Improving the Expression and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers by Targeted Sequence Changes

通过靶向序列改变提高可溶性重组天然样HIV-1包膜糖蛋白三聚体的表达和纯化

Ringe, Rajesh P; Ozorowski, Gabriel; Yasmeen, Anila; Cupo, Albert; Cruz Portillo, Victor M; Pugach, Pavel; Golabek, Michael; Rantalainen, Kimmo; Holden, Lauren G; Cottrell, Christopher A; Wilson, Ian A; Sanders, Rogier W; Ward, Andrew B; Klasse, P J; Moore, John P

Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes

降低非中和表位暴露的稳定化 HIV-1 包膜三聚体的免疫原性

de Taeye, Steven W; Ozorowski, Gabriel; Torrents de la Peña, Alba; Guttman, Miklos; Julien, Jean-Philippe; van den Kerkhof, Tom L G M; Burger, Judith A; Pritchard, Laura K; Pugach, Pavel; Yasmeen, Anila; Crampton, Jordan; Hu, Joyce; Bontjer, Ilja; Torres, Jonathan L; Arendt, Heather; DeStefano, Joanne; Koff, Wayne C; Schuitemaker, Hanneke; Eggink, Dirk; Berkhout, Ben; Dean, Hansi; LaBranche, Celia; Crotty, Shane; Crispin, Max; Montefiori, David C; Klasse, P J; Lee, Kelly K; Moore, John P; Wilson, Ian A; Ward, Andrew B; Sanders, Rogier W