Pui Yan Ho相关文献与解析，生知库 | 链接生命科学的每一步

In vivo fermentation production of humanized noncoding RNAs carrying payload miRNAs for targeted anticancer therapy

体内发酵生产携带有效载荷 miRNA 的人源化非编码 RNA，用于靶向抗癌治疗

Peng-Cheng Li, Mei-Juan Tu, Pui Yan Ho, Neelu Batra, Michelle M L Tran, Jing-Xin Qiu, Theodore Wun, Primo N Lara, Xiang Hu, Ai-Xi Yu, Ai-Ming Yu

肿瘤

Peptide nucleic acid-dependent artifact can lead to false-positive triplex gene editing signals

肽核酸依赖性制品可导致假阳性三链基因编辑信号

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:

doi:10.1073/pnas.2109175118

Pui Yan Ho, Zhen Zhang, Mark E Hayes, Andrew Curd, Carla Dib, Maire Rayburn, Sze Nok Tam, Tumul Srivastava, Brandon Hriniak, Xiao-Jun Li, Scott Leonard, Lan Wang, Somayeh Tarighat, Derek S Sim, Mark Fiandaca, James M Coull, Allen Ebens, Marshall Fordyce, Agnieszka Czechowicz

信号转导

发表日期：2021

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A Novel Bioengineered miR-127 Prodrug Suppresses the Growth and Metastatic Potential of Triple-Negative Breast Cancer Cells

新型生物工程 miR-127 前药可抑制三阴性乳腺癌细胞的生长和转移潜能

期刊:Cancer Research

影响因子:12.5

doi:10.1158/0008-5472.CAN-19-0656

Maxine Umeh-Garcia, Catalina Simion, Pui-Yan Ho, Neelu Batra, Anastasia L Berg, Kermit L Carraway, Aiming Yu, Colleen Sweeney

Bioengineered Let-7c Inhibits Orthotopic Hepatocellular Carcinoma and Improves Overall Survival with Minimal Immunogenicity

生物工程 Let-7c 可抑制原位肝细胞癌，提高总体生存率，且免疫原性最小

期刊:Molecular Therapy-Nucleic Acids

影响因子:6.5

doi:10.1016/j.omtn.2019.01.007

Joseph L Jilek, Qian-Yu Zhang, Mei-Juan Tu, Pui Yan Ho, Zhijian Duan, Jing-Xin Qiu, Ai-Ming Yu

OMMA enables population-scale analysis of complex genomic features and phylogenomic relationships from nanochannel-based optical maps

OMMA能够利用基于纳米通道的光学图谱，对复杂的基因组特征和系统发育基因组关系进行群体规模的分析。

期刊:Gigascience

影响因子:3.9

doi:10.1093/gigascience/giz079

Leung, Alden King-Yung; Liu, Melissa Chun-Jiao; Li, Le; Lai, Yvonne Yuk-Yin; Chu, Catherine; Kwok, Pui-Yan; Ho, Pak-Leung; Yip, Kevin Y; Chan, Ting-Fung

Head and neck squamous cancer progression is marked by CLIC4 attenuation in tumor epithelium and reciprocal stromal upregulation of miR-142-3p, a novel post-transcriptional regulator of CLIC4

头颈部鳞状细胞癌的进展以肿瘤上皮中 CLIC4 的衰减和基质中 miR-142-3p 的上调为标志，miR-142-3p 是一种新型的 CLIC4 转录后调节因子

期刊:Oncotarget

影响因子:

doi:10.18632/oncotarget.27387

Brandi L Carofino, Kayla M Dinshaw, Pui Yan Ho, Christophe Cataisson, Aleksandra M Michalowski, Andrew Ryscavage, Addie Alkhas, Nathan W Wong, Vishal Koparde, Stuart H Yuspa

Bioengineered NRF2-siRNA Is Effective to Interfere with NRF2 Pathways and Improve Chemosensitivity of Human Cancer Cells

生物工程NRF2-siRNA可有效干扰NRF2通路并提高人类癌细胞的化学敏感性

期刊:Drug Metabolism and Disposition

影响因子:4.4

doi:10.1124/dmd.117.078741

Peng-Cheng Li, Mei-Juan Tu, Pui Yan Ho, Joseph L Jilek, Zhijian Duan, Qian-Yu Zhang, Ai-Xi Yu, Ai-Ming Yu

Bioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer Therapy

生物工程非编码 RNA 选择性改变细胞 miRNome 谱以用于癌症治疗

期刊:Journal of Pharmacology and Experimental Therapeutics

影响因子:3.1

doi:10.1124/jpet.118.247775

Pui Yan Ho, Zhijian Duan, Neelu Batra, Joseph L Jilek, Mei-Juan Tu, Jing-Xin Qiu, Zihua Hu, Theodore Wun, Primo N Lara, Ralph W DeVere White, Hong-Wu Chen, Ai-Ming Yu

Nanoradiosensitizer with good tissue penetration and enhances oral cancer radiotherapeutic effect

具有良好组织穿透性并增强口腔癌放射治疗效果的纳米放射增敏剂

In vivo fermentation production of humanized noncoding RNAs carrying payload miRNAs for targeted anticancer therapy

体内发酵生产携带有效载荷 miRNA 的人源化非编码 RNA，用于靶向抗癌治疗

Peptide nucleic acid-dependent artifact can lead to false-positive triplex gene editing signals

肽核酸依赖性制品可导致假阳性三链基因编辑信号

A Novel Bioengineered miR-127 Prodrug Suppresses the Growth and Metastatic Potential of Triple-Negative Breast Cancer Cells

新型生物工程 miR-127 前药可抑制三阴性乳腺癌细胞的生长和转移潜能

Bioengineered Let-7c Inhibits Orthotopic Hepatocellular Carcinoma and Improves Overall Survival with Minimal Immunogenicity

生物工程 Let-7c 可抑制原位肝细胞癌，提高总体生存率，且免疫原性最小

OMMA enables population-scale analysis of complex genomic features and phylogenomic relationships from nanochannel-based optical maps

OMMA能够利用基于纳米通道的光学图谱，对复杂的基因组特征和系统发育基因组关系进行群体规模的分析。

Head and neck squamous cancer progression is marked by CLIC4 attenuation in tumor epithelium and reciprocal stromal upregulation of miR-142-3p, a novel post-transcriptional regulator of CLIC4

头颈部鳞状细胞癌的进展以肿瘤上皮中 CLIC4 的衰减和基质中 miR-142-3p 的上调为标志，miR-142-3p 是一种新型的 CLIC4 转录后调节因子

Bioengineered NRF2-siRNA Is Effective to Interfere with NRF2 Pathways and Improve Chemosensitivity of Human Cancer Cells

生物工程NRF2-siRNA可有效干扰NRF2通路并提高人类癌细胞的化学敏感性

Bioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer Therapy

生物工程非编码 RNA 选择性改变细胞 miRNome 谱以用于癌症治疗