日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Enhancement of anti-sarcoma immunity by NK cells engineered with mRNA for expression of a EphA2-targeted CAR

利用基因工程改造NK细胞,使其表达靶向EphA2的CAR,从而增强抗肉瘤免疫力

Lam, Pui Yeng; Omer, Natacha; Wong, Josh K M; Tu, Cui; Alim, Louisa; Rossi, Gustavo R; Victorova, Maria; Tompkins, Hannah; Lin, Cheng-Yu; Mehdi, Ahmed M; Choo, Amos; Elliott, Melissa R; Coleborn, Elaina; Sun, Jane; Mercer, Timothy; Vittorio, Orazio; Dobson, Lachlan J; McLellan, Alexander D; Brooks, Andrew; Tuong, Zewen Kelvin; Cheetham, Seth W; Nicholls, Wayne; Souza-Fonseca-Guimaraes, Fernando

Assessing spatial sequencing and imaging approaches to capture the molecular and pathological heterogeneity of archived cancer tissues

评估空间测序和成像方法以捕获存档癌症组织的分子和病理异质性

Tuan Vo, P Prakrithi, Kahli Jones, Sohye Yoon, Pui Yeng Lam, Yung-Ching Kao, Ning Ma, Samuel X Tan, Xinnan Jin, Chenhao Zhou, Joanna Crawford, Shaun Walters, Ishaan Gupta, Peter H Soyer, Kiarash Khosrotehrani, Mitchell S Stark, Quan Nguyen

Dichotomous outcomes of TNFR1 and TNFR2 signaling in NK cell-mediated immune responses during inflammation

炎症期间NK细胞介导的免疫反应中TNFR1和TNFR2信号传导的二元结果

Timothy R McCulloch # ,Gustavo R Rossi # ,Louisa Alim # ,Pui Yeng Lam ,Joshua K M Wong ,Elaina Coleborn ,Snehlata Kumari ,Colm Keane ,Andrew J Kueh ,Marco J Herold ,Christoph Wilhelm ,Percy A Knolle ,Lawrence Kane ,Timothy J Wells ,Fernando Souza-Fonseca-Guimaraes

Robust mapping of spatiotemporal trajectories and cell-cell interactions in healthy and diseased tissues

对健康和病变组织中时空轨迹和细胞间相互作用进行稳健的映射

Pham, Duy; Tan, Xiao; Balderson, Brad; Xu, Jun; Grice, Laura F; Yoon, Sohye; Willis, Emily F; Tran, Minh; Lam, Pui Yeng; Raghubar, Arti; Kalita-de Croft, Priyakshi; Lakhani, Sunil; Vukovic, Jana; Ruitenberg, Marc J; Nguyen, Quan H

Spatially Resolved Transcriptomes of Mammalian Kidneys Illustrate the Molecular Complexity and Interactions of Functional Nephron Segments

哺乳动物肾脏的空间分辨转录组阐明了功能性肾元节段的分子复杂性和相互作用

Arti M Raghubar, Duy T Pham, Xiao Tan, Laura F Grice, Joanna Crawford, Pui Yeng Lam, Stacey B Andersen, Sohye Yoon, Siok Min Teoh, Nicholas A Matigian, Anne Stewart, Leo Francis, Monica S Y Ng, Helen G Healy, Alexander N Combes, Andrew J Kassianos, Quan Nguyen, Andrew J Mallett4

Glucocorticoids promote apoptosis of proinflammatory monocytes by inhibiting ERK activity

糖皮质激素通过抑制 ERK 活性促进促炎性单核细胞凋亡

Adrian Achuthan, Ahmad S M Aslam, Quyen Nguyen, Pui-Yeng Lam, Andrew J Fleetwood, Ashlee T Frye, Cynthia Louis, Ming-Chin Lee, Julia E Smith, Andrew D Cook, Moshe Olshansky, Stephen J Turner, John A Hamilton

Therapeutic vaccination with 4-1BB co-stimulation eradicates mouse acute myeloid leukemia

利用 4-1BB 共刺激进行治疗性疫苗接种可根除小鼠急性髓系白血病

Kerage, Daniel; Soon, Megan S F; Doff, Brianna L; Kobayashi, Takumi; Nissen, Michael D; Lam, Pui Yeng; Leggatt, Graham R; Mattarollo, Stephen R

Invariant Natural Killer T Cells in Immune Regulation of Blood Cancers: Harnessing Their Potential in Immunotherapies

不变性自然杀伤T细胞在血液癌症免疫调节中的作用:发挥其在免疫疗法中的潜力

Lam, Pui Yeng; Nissen, Michael D; Mattarollo, Stephen R

B cell lymphoma progression promotes the accumulation of circulating Ly6Clo monocytes with immunosuppressive activity

细胞淋巴瘤进展促进具有免疫抑制活性的循环 Ly6Clo 单核细胞的积累

Sara J McKee, Zewen K Tuong, Takumi Kobayashi, Brianna L Doff, Megan Sf Soon, Michael Nissen, Pui Yeng Lam, Colm Keane, Frank Vari, Davide Moi, Roberta Mazzieri, Graham Leggatt, Maher K Gandhi, Stephen R Mattarollo

Granulocyte macrophage colony-stimulating factor induces CCL17 production via IRF4 to mediate inflammation

粒细胞巨噬细胞集落刺激因子通过IRF4诱导CCL17的产生,从而介导炎症反应。

Adrian Achuthan, Andrew D Cook, Ming-Chin Lee, Reem Saleh, Hsu-Wei Khiew, Melody W N Chang, Cynthia Louis, Andrew J Fleetwood, Derek C Lacey, Anne D Christensen, Ashlee T Frye, Pui Yeng Lam, Hitoshi Kusano, Koji Nomura, Nancy Steiner, Irmgard Förster, Stephen L Nutt, Moshe Olshansky, Stephen J Turner, John A Hamilton