Pujuan相关文献与解析，生知库 | 链接生命科学的每一步

Discovery of YJZ5118: A Potent and Highly Selective Irreversible CDK12/13 Inhibitor with Synergistic Effects in Combination with Akt Inhibition.

YJZ5118 的发现：一种强效且高选择性的不可逆 CDK12/13 抑制剂，与 Akt 抑制剂联合使用具有协同效应

doi:10.1021/acs.jmedchem.5c00127

Yang Jianzhang, Chang Yu, Zhou Kaijie, Huang Weixue, Tien Jean Ching-Yi, Zhang Pujuan, Liu Wenyan, Zhou Licheng, Zhou Yang, Ren Xiaomei, Mannan Rahul, Mahapatra Somnath, Zhang Yuping, Hamadeh Rudana, Ervine Grafton, Wang Zhen, Wang George Xiaoju, Chinnaiyan Arul M, Ding Ke

信号转导

发表日期：2025

文献求助收藏

USP18 attenuates endoplasmic reticulum stress via the PERK-eIF2α-ATF4 axis to reduce apoptosis in hepatocellular carcinoma cells

USP18 通过 PERK-eIF2α-ATF4 轴减弱内质网应激，从而减少肝细胞癌细胞的凋亡。

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-025-00540-2

Li, Lin; Liu, Nana; Yang, Pujuan; Rao, Chunyan; Kong, Lingna; Huang, Yi; Lei, Qingsong; Liu, Huabao

Prenatal ultrasound diagnosis of a rare diffuse placental chorioangioma with fetal edema: a case description and prognostic analysis

产前超声诊断罕见弥漫性胎盘绒毛膜血管瘤伴胎儿水肿：病例描述及预后分析

期刊:Quantitative Imaging in Medicine and Surgery

影响因子:2.3

doi:10.21037/qims-2025-499

Jia, Pujuan; Feng, Xuelu; Cheng, Xiaxia; Wang, Yanzhao; Li, Tiangang; Ma, Bin

发表日期：2025

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Diagnosis of fetal laryngotracheal atresia combined with tracheoesophageal fistula via prenatal ultrasound: a case description

产前超声诊断胎儿喉气管闭锁合并气管食管瘘：病例报告

期刊:Quantitative Imaging in Medicine and Surgery

影响因子:2.3

doi:10.21037/qims-2025-394

Feng, Xuelu; Jia, Pujuan; Cheng, Xiaxia; Ma, Bin

发表日期：2025

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Fetal umbilical-portal-systemic venous shunt diagnosed by prenatal ultrasonography and its association with chromosomal abnormalities

产前超声诊断胎儿脐静脉-门静脉-体循环静脉分流及其与染色体异常的关系

期刊:Quantitative Imaging in Medicine and Surgery

影响因子:2.3

doi:10.21037/qims-2025-486

Li, Chunying; Song, Xiaoyu; Ge, Tingting; Zhang, Chuan; Wang, Xiaozhuan; Qi, Jun; Du, Xiaoning; Hao, Yu; Jia, Pujuan; Wang, Yafei; Lin, Xiaojuan

发表日期：2025

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Prenatal diagnosis of retrorenal left-sided inferior vena cava without hepatic segment using ultrasound and spatiotemporal image correlation: a rare case description

利用超声和时空图像相关性进行肾后左侧下腔静脉（不含肝段）的产前诊断：一例罕见病例报告

期刊:Quantitative Imaging in Medicine and Surgery

影响因子:2.3

doi:10.21037/qims-2024-2468

Jia, Pujuan; Wang, Yanzhao; Zhang, Minhong; Feng, Xuelu; Cheng, Xiaxia; Ma, Bin

发表日期：2025

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Evaluating the efficacy of a continuous comprehensive nursing system on postoperative hemoglobin levels and quality of life in coronary artery bypass surgery: a randomized controlled trial

评估持续综合护理体系对冠状动脉旁路移植术后血红蛋白水平和生活质量的影响：一项随机对照试验

期刊:

影响因子:

doi:10.1186/s13741-025-00621-w

Liu, Pujuan; Xing, Beibei; Wang, Shang; Liu, Huili; Wang, Jing; Zhang, Man; Shen, Hong

发表日期：2025

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Systematic discovery of DNA-binding tandem repeat proteins

DNA 结合串联重复蛋白的系统发现

期刊:Nucleic Acids Research

影响因子:16.6

doi:10.1093/nar/gkae710

Xiaoxuan Hu, Xuechun Zhang, Wen Sun, Chunhong Liu, Pujuan Deng, Yuanwei Cao, Chenze Zhang, Ning Xu, Tongtong Zhang, Yong E Zhang, Jun-Jie Gogo Liu, Haoyi Wang

信号转导

发表日期：2024

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Development of an orally bioavailable CDK12/13 degrader and induction of synthetic lethality with AKT pathway inhibition

开发口服生物可利用的 CDK12/13 降解剂并通过抑制 AKT 通路诱导合成致死

期刊:Cell Reports Medicine

影响因子:11.7

doi:10.1016/j.xcrm.2024.101752

Yu Chang, Xiaoju Wang, Jianzhang Yang, Jean Ching-Yi Tien, Rahul Mannan, Gabriel Cruz, Yuping Zhang, Josh N Vo, Brian Magnuson, Somnath Mahapatra, Hanbyul Cho, Saravana Mohan Dhanasekaran, Cynthia Wang, Zhen Wang, Licheng Zhou, Kaijie Zhou, Yang Zhou, Pujuan Zhang, Weixue Huang, Lanbo Xiao, Weihuang

Prenatal ultrasound diagnosis of fetal cardiac rhabdomyoma and analysis of clinical outcomes

胎儿心脏横纹肌瘤的产前超声诊断及临床结局分析

Discovery of YJZ5118: A Potent and Highly Selective Irreversible CDK12/13 Inhibitor with Synergistic Effects in Combination with Akt Inhibition.

YJZ5118 的发现：一种强效且高选择性的不可逆 CDK12/13 抑制剂，与 Akt 抑制剂联合使用具有协同效应

USP18 attenuates endoplasmic reticulum stress via the PERK-eIF2α-ATF4 axis to reduce apoptosis in hepatocellular carcinoma cells

USP18 通过 PERK-eIF2α-ATF4 轴减弱内质网应激，从而减少肝细胞癌细胞的凋亡。

Prenatal ultrasound diagnosis of a rare diffuse placental chorioangioma with fetal edema: a case description and prognostic analysis

产前超声诊断罕见弥漫性胎盘绒毛膜血管瘤伴胎儿水肿：病例描述及预后分析

Diagnosis of fetal laryngotracheal atresia combined with tracheoesophageal fistula via prenatal ultrasound: a case description

产前超声诊断胎儿喉气管闭锁合并气管食管瘘：病例报告

Fetal umbilical-portal-systemic venous shunt diagnosed by prenatal ultrasonography and its association with chromosomal abnormalities

产前超声诊断胎儿脐静脉-门静脉-体循环静脉分流及其与染色体异常的关系

Prenatal diagnosis of retrorenal left-sided inferior vena cava without hepatic segment using ultrasound and spatiotemporal image correlation: a rare case description

利用超声和时空图像相关性进行肾后左侧下腔静脉（不含肝段）的产前诊断：一例罕见病例报告

Evaluating the efficacy of a continuous comprehensive nursing system on postoperative hemoglobin levels and quality of life in coronary artery bypass surgery: a randomized controlled trial

评估持续综合护理体系对冠状动脉旁路移植术后血红蛋白水平和生活质量的影响：一项随机对照试验

Systematic discovery of DNA-binding tandem repeat proteins

DNA 结合串联重复蛋白的系统发现

Development of an orally bioavailable CDK12/13 degrader and induction of synthetic lethality with AKT pathway inhibition

开发口服生物可利用的 CDK12/13 降解剂并通过抑制 AKT 通路诱导合成致死