日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Time to use the right classification to predict the severity of checkpoint inhibitor-induced liver injury, as assessed for causality using the updated RUCAM

现在是时候采用正确的分类方法来预测免疫检查点抑制剂引起的肝损伤的严重程度了,这可以通过使用更新后的RUCAM评估其因果关系来实现。

Hountondji, Lina; Faure, Stéphanie; Palassin, Pascale; Viel, Philine Witkowski Durand; Dupuy, Marie; Larrey, Dominique; Lamoureux, Anouck; Coustal, Cyrille; Pureur, Dimitri; Lesage, Candice; Assenat, Éric; Rivière, Benjamin; Faillie, Jean-Luc; Quantin, Xavier; Pageaux, Georges-Philippe; Maria, Alexandre Thibault Jacques; Meunier, Lucy

Evaluation of the interest to combine a CD4 Th1-inducer cancer vaccine derived from telomerase and atezolizumab plus bevacizumab in unresectable hepatocellular carcinoma: a randomized non-comparative phase II study (TERTIO - PRODIGE 82)

评估将源自端粒酶的 CD4 Th1 诱导癌症疫苗与阿特珠单抗加贝伐珠单抗联合用于不可切除的肝细胞癌的疗效:一项随机非对照 II 期研究 (TERTIO - PRODIGE 82)

Vienot, Angélique; Jacquin, Marion; Rebucci-Peixoto, Magali; Pureur, Dimitri; Ghiringhelli, François; Assenat, Eric; Hammel, Pascal; Rosmorduc, Olivier; Stouvenot, Morgane; Allaire, Manon; Bouattour, Mohamed; Regnault, Hélène; Fratte, Serge; Raymond, Eric; Soularue, Emilie; Husson-Wetzel, Stéphanie; Di Martino, Vincent; Muller, Allison; Clairet, Anne-Laure; Fagnoni-Legat, Christine; Adotevi, Olivier; Meurisse, Aurélia; Vernerey, Dewi; Borg, Christophe

Signaling mechanisms and disrupted cytoskeleton in the diphenyl ditelluride neurotoxicity

二苯基二碲化物神经毒性中的信号传导机制和细胞骨架破坏

Pessoa-Pureur, Regina; Heimfarth, Luana; Rocha, João B

Exposure of young rats to diphenyl ditelluride during lactation affects the homeostasis of the cytoskeleton in neural cells from striatum and cerebellum

哺乳期幼鼠接触二苯基二碲化物会影响纹状体和小脑神经细胞细胞骨架的稳态

Luana Heimfarth, Karina Pires Reis, Samanta Oliveira Loureiro, Bárbara Ortiz de Lima, João Batista Teixeira da Rocha, Regina Pessoa-Pureur

Homocysteine induces hypophosphorylation of intermediate filaments and reorganization of actin cytoskeleton in C6 glioma cells.

同型半胱氨酸可诱导 C6 胶质瘤细胞中中间丝的低磷酸化和肌动蛋白细胞骨架的重组

Loureiro Samanta Oliveira, Heimfarth Luana, Lacerda Bruna Arcce, Vidal Luiza Fedatto, Soska Angela, dos Santos Natália Gomes, de Souza Wyse Angela Terezinha, Pessoa-Pureur Regina

Thyroid hormones reorganize the cytoskeleton of glial cells through Gfap phosphorylation and Rhoa-dependent mechanisms

甲状腺激素通过Gfap磷酸化和Rhoa依赖性机制重组神经胶质细胞的细胞骨架。

Zamoner, Ariane; Funchal, Cláudia; Jacques-Silva, Maria Caroline; Gottfried, Carmem; Barreto Silva, Fátima Regina Mena; Pessoa-Pureur, Regina

Creatine and antioxidant treatment prevent the inhibition of creatine kinase activity and the morphological alterations of C6 glioma cells induced by the branched-chain alpha-keto acids accumulating in maple syrup urine disease

肌酸和抗氧化剂治疗可预防枫糖尿症中积累的支链α-酮酸引起的肌酸激酶活性抑制和C6胶质瘤细胞形态改变。

Funchal, Cláudia; Schuck, Patrícia Fernanda; Santos, André Quincozes Dos; Jacques-Silva, Maria Caroline; Gottfried, Carmem; Pessoa-Pureur, Regina; Wajner, Moacir

Short-term effects of thyroid hormones on cytoskeletal proteins are mediated by GABAergic mechanisms in slices of cerebral cortex from young rats

在幼鼠大脑皮层切片中,甲状腺激素对细胞骨架蛋白的短期影响是由GABA能机制介导的。

Zamoner, Ariane; Funchal, Cláudia; Heimfarth, Luana; Silva, Fátima R M B; Pessoa-Pureur, Regina

Morphological alterations and cell death provoked by the branched-chain alpha-amino acids accumulating in maple syrup urine disease in astrocytes from rat cerebral cortex

枫糖尿症中积累的支链α-氨基酸引起的鼠脑皮层星形胶质细胞形态改变和细胞死亡

Funchal, Cláudia; Gottfried, Carmem; de Almeida, Lúcia Maria Vieira; dos Santos, André Quincozes; Wajner, Moacir; Pessoa-Pureur, Regina