日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Structure-based Discovery of a Non-competitive FTO Inhibitor Bound to a Cryptic Site at the Domain Interface

基于结构的发现：一种与结构域界面隐蔽位点结合的非竞争性FTO抑制剂

期刊:Journal of Molecular Biology
影响因子:4.5
doi:10.1016/j.jmb.2025.169575
Singh, Aayushi; Pettini, Francesco; Gianibbi, Beatrice; Das, Sayan; Barisani, Donatella; Purslow, Jeffrey A; Furini, Simone; Spiga, Ottavia; Venditti, Vincenzo
发表日期：2026
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The 'ins' and 'outs' of amidines in β-sheet folding and fibril disaggregation

脒类化合物在β-折叠和原纤维解聚中的作用

期刊:Chemical Science
影响因子:7.4
doi:10.1039/d5sc05902j
O'Brien, Emily A; Abbasi, Mohaddeseh; Purslow, Jeffrey A; VanVeller, Brett
发表日期：2025
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Fine-Tuning of ATF4 DNA Binding Activity by a Secondary Basic Motif Unique to the ATF-X Subfamily of bZip Transcription Factors

bZip转录因子ATF-X亚家族特有的二级碱性基序对ATF4 DNA结合活性的精细调控

期刊:Biochemistry
影响因子:3
doi:10.1021/acs.biochem.4c00640
Siang, Steven; Patel, Urval; Chaves-Mejía, Manuela; Purslow, Jeffrey A; Potoyan, Davit; Roche, Julien
ATF4
信号转导
发表日期：2025
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(1)H, (15)N, (13)C backbone resonance assignment of human Alkbh7

人 Alkbh7 的 (1)H、(15)N、(13)C 骨架共振归属

期刊:Biomolecular Nmr Assignments
影响因子:0.6
doi:10.1007/s12104-025-10219-4
Faal, Baboucarr; Purslow, Jeffrey A; Venditti, Vincenzo
发表日期：2025
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An α-ketoglutarate conformational switch controls iron accessibility, activation, and substrate selection of the human FTO protein

α-酮戊二酸构象转换控制着人FTO蛋白的铁可及性、活化和底物选择。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2404457121
Burns, Daniel; Khatiwada, Balabhadra; Singh, Aayushi; Purslow, Jeffrey A; Potoyan, Davit A; Venditti, Vincenzo
发表日期：2024
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GSK3β phosphorylation catalyzes the aggregation of tau into Alzheimer's disease-like filaments

GSK3β磷酸化催化tau蛋白聚集形成类似阿尔茨海默病的丝状结构

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2414176121
Chakraborty, Pijush; Ibáñez de Opakua, Alain; Purslow, Jeffrey A; Fromm, Simon A; Chatterjee, Debdeep; Zachrdla, Milan; Zhuang, Shannon; Puri, Sambhavi; Wolozin, Benjamin; Zweckstetter, Markus
信号转导
阿尔茨海默症
磷酸化
GSK3
发表日期：2024
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Hydrogen-bonding behavior of amidines in helical structure

脒类化合物在螺旋结构中的氢键行为

期刊:Chemical Science
影响因子:7.4
doi:10.1039/d4sc06108j
O'Brien, Emily A; Purslow, Jeffrey A; Wall, Brendan J; VanVeller, Brett
发表日期：2024
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Comparison of the Diagnosis and Management of Demodex Blepharitis Between Eye Care Practitioners in India and Australasia - A Survey-Based Comparison

印度和澳大利亚眼科医生对蠕形螨睑缘炎的诊断和治疗的比较——一项基于调查的研究

期刊:Clinical Optometry
影响因子:1.8
doi:10.2147/OPTO.S469599
Sharma, Nikhil; Martin, Eilidh; Pearce, Edward Ian; Hagan, Suzanne; Purslow, Christine; Craig, Jennifer P
发表日期：2024
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Demodex Blepharitis: A Survey-Based Approach to Investigate Knowledge, Attitudes, and Practices Among Optometrists in India

蠕形螨睑缘炎：一项基于调查的方法，旨在了解印度验光师的知识、态度和实践

期刊:Clinical Optometry
影响因子:1.8
doi:10.2147/OPTO.S403837
Sharma, Nikhil; Martin, Eilidh; Pearce, Edward Ian; Hagan, Suzanne; Purslow, Christine
发表日期：2023
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Solution structure ensemble of human obesity-associated protein FTO reveals druggable surface pockets at the interface between the N- and C-terminal domain

人类肥胖相关蛋白FTO的溶液结构集合揭示了N端和C端结构域界面处存在可成药的表面口袋。

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2022.101907
Khatiwada, Balabhadra; Nguyen, Trang T; Purslow, Jeffrey A; Venditti, Vincenzo
肥胖
代谢
发表日期：2022
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