日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Distal noncontiguous recurrence and sarcomatous transformation of glioblastoma with stable molecular profile: illustrative case

胶质母细胞瘤远端非连续性复发及肉瘤样转化伴稳定分子特征:病例报告

Howran, Jacob; Andrews, Kaytlin; Ogawa, Kana; Cook, Douglas; Purzner, James; Ynoe Moraes, Fabio; Rossiter, John P; Purzner, Teresa

Ezh2 Delays Activation of Differentiation Genes During Normal Cerebellar Granule Neuron Development and in Medulloblastoma.

Ezh2 延迟正常小脑颗粒神经元发育和髓母细胞瘤中分化基因的激活

Purzner James, Brown Alexander S, Purzner Teresa, Ellis Lauren, Broski Sara, Litzenburger Ulrike, Andrews Kaytlin, Sharma Aryaman, Wang Xin, Taylor Michael D, Cho Yoon-Jae, Fuller Margaret T, Scott Matthew P

LC-MS/MS method for quantitation of the CK2 inhibitor silmitasertib (CX-4945) in human plasma, CSF, and brain tissue, and application to a clinical pharmacokinetic study in children with brain tumors.

采用 LC-MS/MS 方法定量分析人血浆、脑脊液和脑组织中的 CK2 抑制剂 silmitasertib (CX-4945),并将其应用于脑肿瘤患儿的临床药代动力学研究

Zhong Bo, Campagne Olivia, Salloum Ralph, Purzner Teresa, Stewart Clinton F

Casein kinase 2 inhibition sensitizes medulloblastoma to temozolomide

酪蛋白激酶 2 抑制剂可使髓母细胞瘤对替莫唑胺敏感

Ryan T Nitta, Sara Bolin, Emily Luo, David E Solow-Codero, Peyman Samghabadi, Teresa Purzner, Parvir S Aujla, Ginikachi Nwagbo, Yoon-Jae Cho, Gordon Li

Developmental phosphoproteomics identifies the kinase CK2 as a driver of Hedgehog signaling and a therapeutic target in medulloblastoma

发育磷酸化蛋白质组学确定激酶 CK2 是 Hedgehog 信号传导的驱动因素,也是髓母细胞瘤的治疗靶点

Teresa Purzner, James Purzner, Taylor Buckstaff, Giorgio Cozza, Sharareh Gholamin, Jessica M Rusert, Tom A Hartl, John Sanders, Nicholas Conley, Xuecai Ge, Marc Langan, Vijay Ramaswamy, Lauren Ellis, Ulrike Litzenburger, Sara Bolin, Johanna Theruvath, Ryan Nitta, Lin Qi, Xiao-Nan Li, Gordon Li, Mich

Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress

髓母细胞瘤相关 DDX3 变体选择性地改变对压力的翻译反应

Sekyung Oh, Ryan A Flynn, Stephen N Floor, James Purzner, Lance Martin, Brian T Do, Simone Schubert, Dedeepya Vaka, Sorana Morrissy, Yisu Li, Marcel Kool, Volker Hovestadt, David T W Jones, Paul A Northcott, Thomas Risch, Hans-Jörg Warnatz, Marie-Laure Yaspo, Christopher M Adams, Ryan D Leib, Marcus

Phosphodiesterase 4D acts downstream of Neuropilin to control Hedgehog signal transduction and the growth of medulloblastoma

磷酸二酯酶 4D 作用于神经纤毛蛋白的下游,控制 Hedgehog 信号转导和髓母细胞瘤的生长

Xuecai Ge, Ljiljana Milenkovic, Kaye Suyama, Tom Hartl, Teresa Purzner, Amy Winans, Tobias Meyer, Matthew P Scott

Involvement of the basal ganglia and cerebellar motor pathways in the preparation of self-initiated and externally triggered movements in humans

基底神经节和小脑运动通路参与人类自主运动和外部触发运动的准备过程

Purzner, Jamie; Paradiso, Guillermo O; Cunic, Danny; Saint-Cyr, Jean A; Hoque, Tasnuva; Lozano, Andres M; Lang, Anthony E; Moro, Elena; Hodaie, Mojgan; Mazzella, Filomena; Chen, Robert