日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Replicon-based genome-wide CRISPR knockout screening for the identification of host factors involved in viral replication.

基于复制子的全基因组 CRISPR 敲除筛选,用于鉴定参与病毒复制的宿主因子。

Cheng Karen W, Bhave Madhura, Markhard Andrew L, Peng Duo, Bhatt Karan D, Travisano Katherine A, Medicielo Josette V, Anaya Astrid, Lembirik Sanae, Njoya Leila, Anantpadma Manu, Kuhn Jens H, Puschnik Andreas S, Kistler Amy L

Therapy with murinized tobevibart and elebsiran is efficacious in a liver-chimeric mouse model of HDV infection

在HDV感染的肝嵌合小鼠模型中,使用鼠源化托贝伐他汀和艾来昔兰进行治疗是有效的。

Zhou, Jiayi; Kaiser, Hannah; Rocha, Evelyn; Terrell, Ashley N; Corti, Davide; Purcell, Lisa A; Lempp, Florian A; Puschnik, Andreas S

Defining the host dependencies and the transcriptional landscape of RSV infection

明确RSV感染的宿主依赖性和转录图谱

Sunshine, Sara; Puschnik, Andreas; Retallack, Hanna; Laurie, Matthew T; Liu, Jamin; Peng, Duo; Knopp, Kristeene; Zinter, Matt S; Ye, Chun Jimmie; DeRisi, Joseph L

Defining the host dependencies and the transcriptional landscape of RSV infection and bystander activation

明确RSV感染和旁观者激活的宿主依赖性和转录图谱

Sunshine, Sara; Puschnik, Andreas; Retallack, Hanna; Laurie, Matthew T; Liu, Jamin; Peng, Duo; Knopp, Kristeene; Zinter, Matt S; Ye, Chun Jimmie; DeRisi, Joseph L

Open-source milligram-scale, four channel, automated protein purification system

开源毫克级四通道自动化蛋白质纯化系统

Robert R Puccinelli, Samia S Sama, Caroline M Worthington, Andreas S Puschnik, John E Pak, Rafael Gómez-Sjöberg

Hardwiring tissue-specific AAV transduction in mice through engineered receptor expression

通过基因工程改造受体表达,在小鼠体内构建组织特异性AAV转导系统。

James Zengel # ,Yu Xin Wang # ,Jai Woong Seo # ,Ke Ning # ,James N Hamilton ,Bo Wu ,Marina Raie ,Colin Holbrook ,Shiqi Su ,Derek R Clements ,Sirika Pillay ,Andreas S Puschnik ,Monte M Winslow ,Juliana Idoyaga ,Claude M Nagamine ,Yang Sun ,Vinit B Mahajan ,Katherine W Ferrara ,Helen M Blau ,Jan E Carette

Systematic functional interrogation of SARS-CoV-2 host factors using Perturb-seq

使用 Perturb-seq 对 SARS-CoV-2 宿主因子进行系统功能研究

Sara Sunshine, Andreas S Puschnik, Joseph M Replogle, Matthew T Laurie, Jamin Liu, Beth Shoshana Zha, James K Nuñez, Janie R Byrum, Aidan H McMorrow, Matthew B Frieman, Juliane Winkler, Xiaojie Qiu, Oren S Rosenberg, Manuel D Leonetti, Chun Jimmie Ye, Jonathan S Weissman, Joseph L DeRisi, Marco Y He

Genome-Scale Analysis of Cellular Restriction Factors That Inhibit Transgene Expression from Adeno-Associated Virus Vectors

抑制腺相关病毒载体转基因表达的细胞限制因子的基因组规模分析

Ashley M Ngo, Andreas S Puschnik

The human disease gene LYSET is essential for lysosomal enzyme transport and viral infection

人类疾病基因LYSET对于溶酶体酶的运输和病毒感染至关重要。

Richards, Christopher M; Jabs, Sabrina; Qiao, Wenjie; Varanese, Lauren D; Schweizer, Michaela; Mosen, Peter R; Riley, Nicholas M; Klüssendorf, Malte; Zengel, James R; Flynn, Ryan A; Rustagi, Arjun; Widen, John C; Peters, Christine E; Ooi, Yaw Shin; Xie, Xuping; Shi, Pei-Yong; Bartenschlager, Ralf; Puschnik, Andreas S; Bogyo, Matthew; Bertozzi, Carolyn R; Blish, Catherine A; Winter, Dominic; Nagamine, Claude M; Braulke, Thomas; Carette, Jan E

Genome-Wide Knockout Screen Identifies Human Sialomucin CD164 as an Essential Entry Factor for Lymphocytic Choriomeningitis Virus

全基因组敲除筛选确定人类唾液粘蛋白 CD164 是淋巴细胞脉络丛脑膜炎病毒的重要进入因子

Jamin Liu, Kristeene A Knopp, Elze Rackaityte, Chung Yu Wang, Matthew T Laurie, Sara Sunshine, Andreas S Puschnik, Joseph L DeRisi