PNKP targeting engages the autophagic machinery through STING and STAT3 to potentiate ferroptosis and chemotherapy in TNBC.
PNKP靶向通过STING和STAT3激活自噬机制,从而增强TNBC中的铁死亡和化疗效果
期刊:Redox Biology
影响因子:11.9
doi:10.1016/j.redox.2025.103775
Maimon Avi, Puzzovio Pier Giorgio, Vinik Yaron, Hannuna Gavriel-David, Donzelli Sara, Rutigliano Daniela, Blandino Giovanni, Lev Sima