Pyne Nigel J相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Interleukin-7 receptor α mutational activation can initiate precursor B-cell acute lymphoblastic leukemia

白细胞介素-7受体α突变激活可启动前体B细胞急性淋巴细胞白血病。

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-021-27197-5

Afonso R M Almeida,João L Neto,Ana Cachucho,Mayara Euzébio,Xiangyu Meng,Rathana Kim,Marta B Fernandes,Beatriz Raposo,Mariana L Oliveira,Daniel Ribeiro,Rita Fragoso,Priscila P Zenatti,Tiago Soares,Mafalda R de Matos,Juliana Ronchi Corrêa,Mafalda Duque,Kathryn G Roberts,Zhaohui Gu,Chunxu Qu,Clara Pereira,Susan Pyne,Nigel J Pyne,Vasco M Barreto,Isabelle Bernard-Pierrot,Emannuelle Clappier,Charles G Mullighan,Ana R Grosso,J Andrés Yunes #,João T Barata #

细胞生物学

发表日期：2021

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A new model for regulation of sphingosine kinase 1 translocation to the plasma membrane in breast cancer cells

乳腺癌细胞鞘氨醇激酶1转位至质膜的新模型

期刊:Journal of Biological Chemistry

doi:10.1016/j.jbc.2021.100674

Ryan D R Brown, Ben E P Veerman, Jeongah Oh, Rothwelle J Tate, Federico Torta, Margaret R Cunningham, David R Adams, Susan Pyne, Nigel J Pyne

发表日期：2021

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Does the Sphingosine 1-Phosphate Receptor-1 Provide a Better or Worse Prognostic Outcome for Breast Cancer Patients?

鞘氨醇-1-磷酸受体-1对乳腺癌患者的预后有好坏之分吗？

期刊:Frontiers in Oncology

影响因子:3.3

doi:10.3389/fonc.2018.00417

Pyne, Nigel J; Pyne, Susan

发表日期：2018

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Native and Polyubiquitinated Forms of Dihydroceramide Desaturase Are Differentially Linked to Human Embryonic Kidney Cell Survival

二氢神经酰胺去饱和酶的天然形式和多泛素化形式与人类胚胎肾细胞存活存在差异

期刊:Molecular and Cellular Biology

影响因子:3.2

doi:10.1128/MCB.00222-18

Mariam Alsanafi, Samuel L Kelly, Karawan Jubair, Melissa McNaughton, Rothwelle J Tate, Alfred H Merrill Jr, Susan Pyne, Nigel J Pyne

发表日期：2018

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The sphingosine 1-phosphate receptor 2 is shed in exosomes from breast cancer cells and is N-terminally processed to a short constitutively active form that promotes extracellular signal regulated kinase activation and DNA synthesis in fibroblasts

鞘氨醇 1-磷酸受体 2 在乳腺癌细胞的外泌体中脱落，并在 N 端加工成短的组成性活性形式，促进成纤维细胞中的细胞外信号调节激酶活化和 DNA 合成

期刊:Oncotarget

doi:10.18632/oncotarget.25658

Ashref El Buri, David R Adams, Douglas Smith, Rothwelle J Tate, Margaret Mullin, Susan Pyne, Nigel J Pyne

细胞生物学

成纤维细胞

发表日期：2018

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Sphingosine 1-Phosphate Receptor 1 Signaling in Mammalian Cells

哺乳动物细胞中的鞘氨醇-1-磷酸受体1信号传导

期刊:Molecules

影响因子:4.6

doi:10.3390/molecules22030344

Pyne, Nigel J; Pyne, Susan

细胞生物学

发表日期：2017

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Sphingosine kinase 2 and multiple myeloma

鞘氨醇激酶2与多发性骨髓瘤

期刊:Oncotarget

doi:10.18632/oncotarget.17420

Pyne, Nigel J; Pyne, Susan

多发性骨髓瘤

发表日期：2017

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Effect of the sphingosine kinase 1 selective inhibitor, PF-543 on arterial and cardiac remodelling in a hypoxic model of pulmonary arterial hypertension

鞘氨醇激酶 1 选择性抑制剂 PF-543 对缺氧肺动脉高压模型中动脉和心脏重塑的影响

期刊:Cellular Signalling

影响因子:4.4

doi:10.1016/j.cellsig.2016.03.014

Neil MacRitchie, Giora Volpert, Mohammed Al Washih, David G Watson, Anthony H Futerman, Simon Kennedy, Susan Pyne, Nigel J Pyne

发表日期：2016

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Novel sphingosine-containing analogues selectively inhibit sphingosine kinase (SK) isozymes, induce SK1 proteasomal degradation and reduce DNA synthesis in human pulmonary arterial smooth muscle cells

新型含鞘氨醇类似物选择性抑制鞘氨醇激酶（SK）同工酶，诱导SK1蛋白酶体降解，并降低人肺动脉平滑肌细胞中的DNA合成。

期刊:Medchemcomm

doi:10.1039/C3MD00201B

Byun, Hoe-Sup; Pyne, Susan; Macritchie, Neil; Pyne, Nigel J; Bittman, Robert

细胞生物学

发表日期：2013

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Sphingosine 1-phosphate receptors and sphingosine kinase 1: novel biomarkers for clinical prognosis in breast, prostate, and hematological cancers

鞘氨醇-1-磷酸受体和鞘氨醇激酶1：乳腺癌、前列腺癌和血液肿瘤临床预后的新型生物标志物

期刊:Frontiers in Oncology

影响因子:3.3

doi:10.3389/fonc.2012.00168

Pyne, Susan; Edwards, Joanne; Ohotski, Jan; Pyne, Nigel J

发表日期：2012

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