日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Trimbody with rigid AI-designed scaffolds enables atomic-resolution cryo-EM structure determination of small proteins

利用人工智能设计的刚性支架构建的Trimbody能够实现小蛋白的原子分辨率冷冻电镜结构解析。

Song, Jinyang; Qi, Lei; Li, Yongyue; Zhang, Xue; He, Yushu; Zhang, Zhengshi; He, Dongfang; Gu, Mengjun; Guan, Yuyao; Fang, Hao; Hou, Xuben; Li, Zengpeng; Wang, Wei

Engineered M2 macrophage-derived extracellular vesicles reprogram mitochondrial metabolism to alleviate temporomandibular joint cartilage degeneration.

工程化的 M2 巨噬细胞衍生的细胞外囊泡重编程线粒体代谢,以缓解颞下颌关节软骨退化。

Ge Weiwen, Qi Lei, Wang Yun, Wang Jing, Fang Xin, Lei Shixue, Lin Dan, Zhang Lei, Zhang Shanyong

Disulfidptosis-related genes define a prognostic signature and novel therapeutic targets in Ewing's sarcoma through transcriptomic analysis and experimental validation

通过转录组分析和实验验证,二硫键凋亡相关基因定义了尤文氏肉瘤的预后特征和新的治疗靶点。

Wang, Zhenyang; Chen, Yongqin; Yang, Yuxuan; Qi, Lei; Xu, Biteng; Li, Ke; Wang, Liang; Jiao, Xiejia

Subcellular Structures in Native Hippocampal Synapses Revealed by Cryo-electron Tomography

冷冻电镜断层扫描揭示天然海马突触的亚细胞结构

Tian, Chong-Li; Qi, Lei; Lu, Zhen-Hang; Liu, Shuo; Gu, Min-Ling; Huang, Wen-Lan; Yan, Yi-Tong; Liu, Yun-Tao; Wu, Jing; Wang, Peiyi; Zhou, Z Hong; Bi, Guo-Qiang; Lau, Pak-Ming; Tao, Chang-Lu

A CRISPR-Cas13d cancer therapeutic enables selective elimination of uveal melanoma

一种 CRISPR-Cas13d 癌症疗法能够选择性地消除葡萄膜黑色素瘤

Stauber, Daniel; Sosnick, Lucas; Ma, Yitong; Pimcharoen, Sopida; Lawanprasert, Atip; Murthy, Niren; Myung, David; Qi, Lei S

Rewriting the epigenome: CRISPR tools for biological discovery and therapeutics

重写表观基因组:CRISPR工具在生物学发现和治疗中的应用

Otero, Christian P; Qi, Lei S

Effect of the BOPPPS-based blended teaching model in undergraduate nursing education: a quasi-experimental study

基于BOPPPS的混合式教学模式在本科护理教育中的效果:一项准实验研究

Dai, Yehua; He, Qi; Lei, Lixia

Putative long range mossy fiber sprouting and regional cytochrome c oxidase alteration in the hippocampus of patients with mesial temporal lobe epilepsy.

内侧颞叶癫痫患者海马中假定的长程苔藓纤维萌发和区域细胞色素c氧化酶改变。

Tu Tian, Wan Lily, Zhang Qi-Lei, Yang Chen, Zhou Hong-Shu, Sun Zhong-Ping, Long Hong-Yu, Tang Bei-Sha, Pan Aihua, Tu Ewen, Wang Jian, Yang Zhi-Quan, Li Zhen-Yan, Yan Xiao-Xin

The Safety and Efficacy of Unilateral Biportal Endoscopic Decompression for the Treatment of Thoracic Ossification of Ligamentum Flavum with Occupancy Ratio > 60%: A Retrospective Cohort Study

单侧双通道内镜减压术治疗胸椎黄韧带骨化(占位率>60%)的安全性和有效性:一项回顾性队列研究

Qi, Lei; Xu, Biteng; Guo, Xiangji; Yu, Gaoya; Yang, Yuxuan; Yu, Haozhi; Wang, Liang

Research progress in the application of stent in TIPS procedures

TIPS手术中支架应用的研究进展

Qi, Lei; Wang, Yihao; Li, Wen; Li, Shuangshuang; Zhou, Jian