Gasdermin-E-mediated pyroptosis drives immune checkpoint inhibitor-associated myocarditis via cGAS-STING activation
Gasdermin-E介导的细胞焦亡通过cGAS-STING激活驱动免疫检查点抑制剂相关性心肌炎。
期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-024-50996-5
Si-Jia Sun #,Xiao-Dong Jiao #,Zhi-Gang Chen #,Qi Cao #,Jia-Hui Zhu,Qi-Rui Shen,Yi Liu,Zhen Zhang,Fang-Fang Xu,Yu Shi,Jie Tong,Shen-Xi Ouyang,Jiang-Tao Fu,Yi Zhao,Jun Ren,Dong-Jie Li,Fu-Ming Shen,Pei Wang
心肌炎
细胞生物学
炎症/感染
免疫/内分泌
CGAS
STING
Checkpoint
焦亡
