Lysosomal EGFR acts as a Rheb-GEF independent of its kinase activity to activate mTORC1.
溶酶体 EGFR 作为一种 Rheb-GEF，不依赖于其激酶活性，即可激活 mTORC1
期刊:Cell Research
影响因子:25.9
doi:10.1038/s41422-025-01110-x
He Xiaobo, Wang Qiu-Xia, Wei Denghui, Lin Yujie, Zhang Xia, Wu Yuanzhong, Qian Xuexia, Lin Zhihao, Xiao Beibei, Wu Qinxue, Wang Zhen, Zhou Fengtao, Wei Zhihao, Wang Jingxuan, Gong Run, Zhang Ruhua, Zhang Qingling, Ding Ke, Gao Song, Kang Tiebang
