日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

KRASG12D-driven pentose phosphate pathway remodeling imparts a targetable vulnerability synergizing with MRTX1133 for durable remissions in PDAC

KRASG12D 驱动的戊糖磷酸途径重塑赋予可靶向的脆弱性，与 MRTX1133 协同作用，实现 PDAC 的持久缓解

期刊:Cell Reports Medicine
影响因子:11.7
doi:10.1016/j.xcrm.2025.101966
Xiangyan Jiang, Tao Wang, Bin Zhao, Haonan Sun, Yuman Dong, Yong Ma, Zhigang Li, Yuxia Wu, Keshen Wang, Xiaoying Guan, Bo Long, Long Qin, Wengui Shi, Lei Shi, Qichen He, Wenbo Liu, Mingdou Li, Lixia Xiao, Chengliang Zhou, Hui Sun, Jing Yang, Junhong Guan, Huinian Zhou, Zeyuan Yu, Zuoyi Jiao1
RAS
发表日期：2025
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CCT020312 exerts anti-prostate cancer effect by inducing G1 cell cycle arrest, apoptosis and autophagy through activation of PERK/eIF2α/ATF4/CHOP signaling

CCT020312 通过激活 PERK/eIF2α/ATF4/CHOP 信号诱导 G1 细胞周期停滞、细胞凋亡和自噬，发挥抗前列腺癌作用

期刊:Biochemical Pharmacology
影响因子:5.3
doi:10.1016/j.bcp.2024.116038
Duanfang Zhou, Manjialan Yin, Baoguo Kang, Xiaoping Yu, Hongfang Zeng, Bo Chen, Gang Wang, Yi Song, Xu Liu, Qichen He, Qiuya Wu, Limei Zhang, Lihong Wu, Yuanli Wu, Na Qu, Xiaoli Li, Weiying Zhou
信号转导
细胞生物学
肿瘤
前列腺癌
其它细胞
Apoptosis
Autophagy
MAPK/ERK
发表日期：2024
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Targeting the mevalonate pathway enhances the efficacy of 5-fluorouracil by regulating pyroptosis

靶向甲羟戊酸途径可通过调节细胞焦亡来增强 5-氟尿嘧啶的疗效

期刊:Medical Oncology
影响因子:2.8
doi:10.1007/s12032-024-02557-5
Zongrui Xing #, Yong Ma #, Xiangyan Jiang #, Huiguo Qing #, Yuxia Wu, Shengfu Che, Zhongti Gao, Keshen Wang, Tao Wang, Qichen He, Zhigang Li, Bin Zhao, Wenbo Liu, Haonan Sun, Zeyuan Yu
免疫
细胞生物学
其它细胞
发表日期：2024
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A case report of a bleeding case after removal of chest drain after lung surgery

肺部手术后拔除胸腔引流管后出血病例报告

期刊:Medicine
影响因子:1.4
doi:10.1097/MD.0000000000039279
Liang, Qichen; He, Baoyu; Zhang, Bin; Zhang, Ziteng
发表日期：2024
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Ginsenoside Rh2 suppresses colon cancer growth by targeting the miR-150-3p/SRCIN1/Wnt axis

人参皂苷 Rh2 通过靶向 miR-150-3p/SRCIN1/Wnt 轴抑制结肠癌生长

期刊:Acta Biochimica et Biophysica Sinica
影响因子:
doi:10.3724/abbs.2023032
Shipeng Li, Wenfeng Han, Qichen He, Yang Wang, Gang Jin, Youcheng Zhang
信号转导
肿瘤
肠癌
WB
Wnt/β-Catenin
发表日期：2023
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Co-Crystal of Rosiglitazone With Berberine Ameliorates Hyperglycemia and Insulin Resistance Through the PI3K/AKT/TXNIP Pathway In Vivo and In Vitro

罗格列酮与小檗碱的共晶体通过 PI3K/AKT/TXNIP 通路在体内和体外改善高血糖和胰岛素抵抗

期刊:Frontiers in Pharmacology
影响因子:4.4
doi:10.3389/fphar.2022.842879
Qichen He, Bo Chen, Gang Wang, Duanfang Zhou, Hongfang Zeng, Xiaoli Li, Yi Song, Xiaoping Yu, Wenxin Liang, Huiling Chen, Xu Liu, Qiuya Wu, Lihong Wu, Limei Zhang, Huizhen Li, Xiangnan Hu, Weiying Zhou
信号转导
Insulin Receptor
PI3K/Akt
发表日期：2022
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Quercetin Suppresses Human Glioblastoma Migration and Invasion via GSK3β/β-catenin/ZEB1 Signaling Pathway

槲皮素通过 GSK3β/β-catenin/ZEB1 信号通路抑制人类胶质母细胞瘤迁移和侵袭

期刊:Frontiers in Pharmacology
影响因子:4.4
doi:10.3389/fphar.2022.963614
Bo Chen, Xiaoli Li, Lihong Wu, Duanfang Zhou, Yi Song, Limei Zhang, Qiuya Wu, Qichen He, Gang Wang, Xu Liu, Hui Hu, Weiying Zhou
信号转导
其它细胞
HTRF
Wnt/β-Catenin
Human
发表日期：2022
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Screening of and mechanism underlying the action of serum- and glucocorticoid-regulated kinase 3-targeted drugs against estrogen receptor-positive breast cancer

血清和糖皮质激素调节激酶3靶向药物治疗雌激素受体阳性乳腺癌的筛选及作用机制

期刊:European Journal of Pharmacology
影响因子:4.2
doi:10.1016/j.ejphar.2022.174982
Duanfang Zhou, Xiaoping Yu, Yi Song, Hongfang Zeng, Huan Zhang, Bo Chen, Yalan Wang, Hongyao Li, Xu Liu, Qichen He, Xiaoli Li, Weiying Zhou
肿瘤
乳腺癌
发表日期：2022
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Pharmacological inhibition of SRC-1 phase separation suppresses YAP oncogenic transcription activity

药理学抑制SRC-1相分离可抑制YAP致癌转录活性。

期刊:Cell Research
影响因子:25.9
doi:10.1038/s41422-021-00504-x
Zhu, Guangya; Xie, Jingjing; Fu, Zhenzhen; Wang, Mingliang; Zhang, Qichen; He, Hao; Chen, Zijun; Guo, Xin; Zhu, Jidong
肿瘤
肿瘤免疫
SRC
YAP
相分离
发表日期：2021
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Large thermoelectric power factor from crystal symmetry-protected non-bonding orbital in half-Heuslers

半赫斯勒合金中晶体对称性保护的非键轨道具有较大的热电功率因子

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-018-03866-w
Zhou, Jiawei; Zhu, Hangtian; Liu, Te-Huan; Song, Qichen; He, Ran; Mao, Jun; Liu, Zihang; Ren, Wuyang; Liao, Bolin; Singh, David J; Ren, Zhifeng; Chen, Gang
发表日期：2018
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