Inhibition of CRM1 reverses hypoxia-driven chemoresistance in acute myeloid leukemia via overcoming HIF-1α-mediated lysosomal sequestration.

抑制 CRM1 可克服 HIF-1α 介导的溶酶体隔离，从而逆转急性髓系白血病中缺氧驱动的化疗耐药性。