文献库，生知库 | 链接生命科学的每一步

日期影响因子

ROS-responsive, brain- and M1 microglia-targeting modified ginkgetin-loaded smart liposomes ameliorate cerebral ischemia by HIF-1Î±-mediated negative regulation of microglia pyroptosis.

ROS 响应性、靶向脑和 M1 小胶质细胞的修饰银杏黄素负载智能脂质体通过 HIF-1α 介导的小胶质细胞焦亡的负调控来改善脑缺血。

期刊:Materials Today Bio

影响因子:10.2

doi:10.1016/j.mtbio.2026.102870

Li Xueyuan, Ye Zi, Nie Wenyang, Zhou Bao, Qin Haocheng, Zhao Zhijie, Fu Yilong, Liu Dun, Zheng Shaowei, Wang Liangyu, Ma Jun, Guo Jingying, Nie Beibei, Lu Yan, Yan Dongming, Luo Zhiwen, Wang Qingshan, Bian Meng, Jiang Hui, Chen Di

细胞生物学

发表日期：2026

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Bioactive siRNA-Based Liposomes Promoted Tendon-Bone Healing in Osteoporotic Mice by Recovering the Stemness of CD248(+) TSPCs

基于生物活性siRNA的脂质体通过恢复CD248(+) TSPC的干性促进骨质疏松小鼠的肌腱-骨愈合

期刊:Advanced Science

影响因子:14.1

doi:10.1002/advs.202509883

Qian, Yinhua; Zhu, Jinguo; He, Yanwei; Qin, Haocheng; Qian, Pingkang; Sun, Bingfeng; Huang, Haoqiang; Kuang, Chen; Yang, Quan; Ou, Yuxi; Sun, Rong; Xu, Feng; Wang, Xianwen; Luo, Zhiwen; Wang, Qing

发表日期：2025

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Neuron-targeted ROS-responsive liposomes for puerarin delivery remodel ischemic microenvironment via microglial modulation and neurovascular regeneration.

靶向神经元的 ROS 响应脂质体用于葛根素递送，通过小胶质细胞调节和神经血管再生重塑缺血微环境。

期刊:Journal of Nanobiotechnology

影响因子:12.6

doi:10.1186/s12951-025-03730-2

Chen Di, Jiang Hui, Sun Lu, Nurzat Yeltai, Qin Haocheng, Zhao Zhijie, Liu Dun, Zheng Shaowei, Wang Liangyu, Fu Yilong, Jiao Henan, Zhu Xuqiang, Song Bo, Yang Jinghua, Lin Zhiheng, Chen Yisheng, Luo Zhiwen, Xu Yuming, Yan Dongming, Zhao ZhenZhen, Li Shaohua

细胞生物学

发表日期：2025

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Enriched Environment Ameliorates Cerebral Ischemia-Reperfusion Injury via Dopamine-H(2)S Axis-Mediated Dual Mitophagy Activation.

富集环境通过多巴胺-H(2)S轴介导的双重线粒体自噬激活改善脑缺血再灌注损伤。

期刊:Antioxidants

影响因子:6.6

doi:10.3390/antiox15010052

Zhou Bao, Qin Haocheng, Yang Pengkun, Ren Na, Sun Lu, Ding Zhengran, He Zhong, Zhang Shuai, Hua Zijian, Zheng Ya, Li Ce, Kuang Shenyi, Zhu Yulian, Yu Kewei

发表日期：2025

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Remote Ischemic Postconditioning Improve Cerebral Ischemia-Reperfusion InjuryÂ Induced Cognitive Dysfunction through Suppressing Mitochondrial Apoptosis in Hippocampus via TK/BK/B2R-Mediated PI3K/AKT.

远程缺血后处理通过 TK/BK/B2R 介导的 PI3K/AKT 抑制海马线粒体凋亡，改善脑缺血再灌注损伤引起的认知功能障碍

期刊:Molecular Neurobiology

影响因子:4.3

doi:10.1007/s12035-025-04864-y

Qin Haocheng, Su Lu, Zhou Bao, Yang Pengkun, Zhu Yu-Lian, Liang Dan

发表日期：2025

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Remote Ischemic Postconditioning Protects the Neurovascular Units in MCAO/R Rats through HIF-1Î±-Mediated Pathway.

远程缺血后处理通过 HIF-1α 介导的途径保护 MCAO/R 大鼠的神经血管单元

期刊:ACS Omega

影响因子:4.3

doi:10.1021/acsomega.4c11416

Qin Haocheng, Sun Lu, Su Lu, Zhou Bao, He Zhong, Yang Pengkun, Ding Zhengran, Zhu Yu-Lian, Liang Dan

发表日期：2025

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Synergistic Therapeutic Platform Combining Transcranial Low-Intensity Ultrasound Stimulation and Curcumin Load Liposome Ameliorates Cerebral Ischemia by Modulating Microglia Polarization-Mediated Neuroinflammatory Microenvironment

结合经颅低强度超声刺激和姜黄素脂质体的协同治疗平台通过调节小胶质细胞极化介导的神经炎症微环境来改善脑缺血

doi:10.34133/research.0861

Qin, Haocheng; Chen, Di; Zhou, Bao; Yang, Pengkun; Zheng, Ya; Sun, Lu; Ding, Zhengran; He, Zhong; Zhang, Shuai; Hua, Zijian; Chen, Gang; Luo, Zhiwen; Zhu, Yulian; Wu, Yi

细胞生物学

发表日期：2025

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Drug Release from Gelsolin-Targeted Phase-Transition Nanoparticles Triggered by Low-Intensity Focused Ultrasound

低强度聚焦超声触发凝溶胶蛋白靶向相变纳米颗粒的药物释放

期刊:International Journal of Nanomedicine

影响因子:6.5

doi:10.2147/IJN.S341421

Qin, Haocheng; Teng, Rong; Liu, Yan; Li, Juan; Yu, Ming

发表日期：2022

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Exercise-induced IL-15 acted as a positive prognostic implication and tumor-suppressed role in pan-cancer

运动诱导的IL-15在泛癌中发挥积极的预后作用和肿瘤抑制作用。

期刊:Frontiers in Pharmacology

影响因子:4.8

doi:10.3389/fphar.2022.1053137

Luo, Zhiwen; He, Zhong; Qin, Haocheng; Chen, Yisheng; Qi, Beijie; Lin, Jinrong; Sun, Yaying; Sun, Junming; Su, Xiaoping; Long, Ziwen; Chen, Shiyi

发表日期：2022

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The therapeutic effects of low-intensity pulsed ultrasound in musculoskeletal soft tissue injuries: Focusing on the molecular mechanism

低强度脉冲超声治疗肌肉骨骼软组织损伤的疗效：聚焦分子机制

期刊:Frontiers in Bioengineering and Biotechnology

影响因子:4.8

doi:10.3389/fbioe.2022.1080430

Qin, Haocheng; Du, Liang; Luo, Zhiwen; He, Zhong; Wang, Qing; Chen, Shiyi; Zhu, Yu-Lian

发表日期：2022

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