Deletion of Tfap2a in hepatocytes and macrophages promotes the progression of hepatocellular carcinoma by regulating SREBP1/FASN/ACC pathway and anti-inflammatory effect of IL10.
肝细胞和巨噬细胞中 Tfap2a 的缺失通过调节 SREBP1/FASN/ACC 通路和 IL10 的抗炎作用促进肝细胞癌的进展
期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-025-07500-8
Li Zhiwei, Zhang Chun, Huang Guixiang, Zhang Zixin, Wang Qinghao, Liu Xiran, Qin Yanling, Zhou Hao, Hou Anyi, He Jun, Li Limin, Hu Xiang, Ding Xiaofeng