Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-kappaB and MAPK signaling pathways.
卡瓦根中的肝毒性成分黄酮卡瓦因 B 通过调节 IKK/NF-kappaB 和 MAPK 信号通路诱导 GSH 敏感的氧化应激
期刊:FASEB Journal
影响因子:4.2
doi:10.1096/fj.10-163311
Zhou Ping, Gross Shimon, Liu Ji-Hua, Yu Bo-Yang, Feng Ling-Ling, Nolta Jan, Sharma Vijay, Piwnica-Worms David, Qiu Samuel X