日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Three mammalian VDAC isoforms distinctly regulate mitochondrial function and proteome to maintain cell metabolism.

三种哺乳动物VDAC同工型分别调节线粒体功能和蛋白质组,以维持细胞代谢。

Rajendran Megha, Rosencrans William M, Bautista Nina A, Fitzgerald Wendy, Huynh Diana, Beyene Bethel G, Quan Baiyi, Petersen Jennifer D, Hwang Julie, Chou Tsui-Fen, Bezrukov Sergey M, Rostovtseva Tatiana K

Fertilization triggers early proteomic symmetry breaking in mammalian embryos.

受精会引发哺乳动物胚胎早期蛋白质组对称性的破坏。

Iwamoto-Stohl Lisa K, Petelski Aleksandra A, Quan Baiyi, Meglicki Maciej, Fu Audrey, Nakagawa Shoma, McMahon Breanna, Wang Ting-Yu, Khan Saad, Specht Harrison, Huffman Gray, Derks Jason, Junyent Sergi, Weatherbee Bailey A T, Weberling Antonia, Gantner Carlos W, Mandelbaum Rachel S, Paulson Richard J, Lam Lisa, Chou Tsui-Fen, Slavov Nikolai, Zernicka-Goetz Magdalena

The gut microbiome promotes mitochondrial respiration in the brain of a Parkinson's disease mouse model.

肠道微生物群促进帕金森病小鼠模型大脑中的线粒体呼吸作用。

Morais Livia H, Stiles Linsey, Freeman Milla, Oguienko Anastasiya D, Hoang Jonathan D, Ji Jenny, Jones Jeff, Quan Baiyi, Devine Jack, Bois Justin S, Chou Tsui-Fen, Trinh Joanne, Picard Martin, Gradinaru Viviana, Mazmanian Sarkis K

Covalent inhibition of Plasmodium falciparum Ubc13 impairs global protein synthesis.

疟原虫 Ubc13 的共价抑制会损害整体蛋白质合成

Truong Anna, Hu Ruitian, Quan Baiyi, Bailey Morgan A, Schroeder Erin A, Sylvester Kayla, Neveu Gaëlle, Kafsack Björn F C, Fitzgerald Michael C, Derbyshire Emily R

Discovery of Host-Directed Small Molecules with Broad Anti-Leishmanial Efficacy

发现具有广谱抗利什曼原虫功效的宿主导向型小分子

Gurysh, Elizabeth G; Zahid, M Shamim Hasan; Johnson, Monica M; Landavazo, Antonio; Namjoshi, Ojas A; Wilson, Joseph W; Varma, Devika M; Woodring, Ryan N; Hendricksen, Aaron T; Vath, Joseph F; Quan, Baiyi; Pino, Erica N; Fitzgerald, Michael C; Bachelder, Eric M; Blough, Bruce E; Ainslie, Kristy M

Unlocking the Distinct Roles of the Three Mammalian VDAC Isoforms in Mitochondrial Respiration and Cancer Cell Metabolism.

揭示三种哺乳动物 VDAC 同工酶在细胞线粒体呼吸和癌细胞代谢中的不同作用

Rajendran Megha, Rosencrans William M, Fitzgerald Wendy, Huynh Diana, Beyene Bethel G, Quan Baiyi, Hwang Julie, Bautista Nina A, Chou Tsui-Fen, Bezrukov Sergey M, Rostovtseva Tatiana K

Selective targeting of Plasmodium falciparum Hsp90 disrupts the 26S proteasome.

选择性靶向恶性疟原虫 Hsp90 可破坏 26S 蛋白酶体

Mansfield Christopher R, Quan Baiyi, Chirgwin Michael E, Eduful Benjamin, Hughes Philip F, Neveu Gaëlle, Sylvester Kayla, Ryan Daniel H, Kafsack Björn F C, Haystead Timothy A J, Leahy James W, Fitzgerald Michael C, Derbyshire Emily R

Quantitative profiling of PTM stoichiometry by resolvable mass tags

利用可分辨质量标签对PTM化学计量比进行定量分析

Chen, Ying; Quan, Baiyi; Li, Yuanpei; Liu, Yuan; Qin, Wei; Wang, Chu

Chemoproteomic-enabled characterization of small GTPase Rab1a as a target of an N-arylbenzimidazole ligand's rescue of Parkinson's-associated cell toxicity

利用化学蛋白质组学方法对小GTP酶Rab1a进行表征,发现N-芳基苯并咪唑配体可挽救帕金森病相关细胞毒性。

Hatstat, A Katherine; Quan, Baiyi; Bailey, Morgan A; Fitzgerald, Michael C; Reinhart, Michaela C; McCafferty, Dewey G

Comparative Analysis of Mass-Spectrometry-Based Proteomic Methods for Protein Target Discovery Using a One-Pot Approach

利用一锅法对基于质谱的蛋白质组学方法在蛋白质靶标发现中的应用进行比较分析

Cabrera, Aurora; Wiebelhaus, Nancy; Quan, Baiyi; Ma, Renze; Meng, He; Fitzgerald, Michael C