日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification of Small-Molecule Inhibitors that Block the GTP-Binding Pocket of K-Ras and Other Members of the Ras Superfamily of Small GTPases

鉴定能够阻断K-Ras及其他Ras超家族小GTP酶成员GTP结合口袋的小分子抑制剂

Carta, Luca; Hutcheson, Rebecca; Bigarella, Carolina L; Zhang, Sufang; Davis, Simon A; Rudolph, Michael J; Reynolds, Charles H; Quick, Matthias; Williams, Theresa M; Schmertzler, Michael; Hadari, Yaron R

Mechanistic snapshots of lipid-linked sugar transfer

脂质连接糖转移的机制快照

Morgan, Ryan T; Motta, Stefano; Gil-Iturbe, Eva; Bhattacharjee, Biddut; Anwar, Mohammad T; Di Muccio, Giovanni; Romagnoli, Alice; Mishra, Bedangshu; Ashraf, Khuram U; Bang, Injin; Di Marino, Daniele; Lowary, Todd L; Quick, Matthias; Petrou, Vasileios I; Stowell, Michael H B; Nygaard, Rie; Mancia, Filippo

Impact of anionic lipids on the energy landscape of conformational transition in anion exchanger 1 (AE1)

阴离子脂质对阴离子交换剂 1 (AE1) 构象转变能量景观的影响

Chen, Tianle; Vallese, Francesca; Gil-Iturbe, Eva; Kim, Kookjoo; Calì, Tito; Quick, Matthias; Clarke, Oliver B; Tajkhorshid, Emad

Effects of the Quinone Analog Ubiquinone-5 on Murine Mitochondria and Hypnosis.

醌类似物泛醌-5对小鼠线粒体和催眠的影响

Somnay Yash R, Wang Aili, Lim Haeun, Griffiths Keren K, Zandkarimi Fereshteh, Chen Kai, Yang Guang, Wasilczuk Andrzej Z, Kelz Max B, Larr David, Yang Mu, Gil-Iturbe Eva, Moon Anna, Quick Matthias, Levy Richard J

A comparative analysis reveals electrogenic properties of PfCRT and pendrin

比较分析揭示了 PfCRT 和 pendrin 的电致特性

Gil-Iturbe, Eva; Quick, Matthias

Collateral hypersensitivity between ZY19489 and piperaquine neutralizes PfCRT-mediated drug efflux and Plasmodium falciparum resistance

ZY19489 与哌喹之间的协同超敏反应可中和 PfCRT 介导的药物外排和恶性疟原虫耐药性。

Okombo, John; Ndiaye, Tolla; Qahash, Tarrick; Moura, Igor M R; Gil-Iturbe, Eva; Hagenah, Laura M; Bridgford, Jessica L; Bonatto, Vinicius; Ward, Kurt E; Yeo, Tomas; Narwal, Sunil K; Orta, Lily V; Anderson, Isla; Dhingra, Satish K; Pasaje, Charisse Flerida A; Park, Heekuk; Kim, Jonathan; Guido, Rafael V C; Angulo-Barturen, Iñigo; Niles, Jacquin C; Mancia, Filippo; Uhlemann, Anne-Catrin; Mok, Sachel; Quick, Matthias; Winzeler, Elizabeth A; Leroy, Didier; Llinás, Manuel; Thathy, Vandana; Fidock, David A

Sexually dimorphic mechanisms of VGLUT-mediated protection from dopaminergic neurodegeneration

VGLUT介导的多巴胺能神经退行性变保护机制存在性别二态性

Buck, Silas A; Rubin, Sophie A; Kunkhyen, Tenzin; Treiber, Christoph D; Xue, Xiangning; Fenno, Lief E; Mabry, Samuel J; Sundar, Varun R; Yang, Zilu; Shah, Divia; Ketchesin, Kyle D; Becker-Krail, Darius D; Vasylieva, Iaroslavna; Smith, Megan C; Weisel, Florian J; Wang, Wenjia; Erickson-Oberg, M Quincy; O'Leary, Emma I; Aravind, Eshan; Ramakrishnan, Charu; Kim, Yoon Seok; Wu, Yanying; Quick, Matthias; Coleman, Jonathan A; MacDonald, William A; Elbakri, Rania; Olsen, Abby L; Rocha, Emily M; Miller, Gary W; De Miranda, Briana R; Palladino, Michael J; McCabe, Brian D; Fish, Kenneth N; Seney, Marianne L; Rayport, Stephen; Mingote, Susana; Deisseroth, Karl; Hnasko, Thomas S; Awatramani, Rajeshwar; Watson, Alan M; Waddell, Scott; Cheetham, Claire E J; Logan, Ryan W; Freyberg, Zachary

Structural and molecular basis of choline uptake into the brain by FLVCR2.

FLVCR2介导的胆碱进入大脑的结构和分子基础

Cater Rosemary J, Mukherjee Dibyanti, Gil-Iturbe Eva, Erramilli Satchal K, Chen Ting, Koo Katie, Santander Nicolás, Reckers Andrew, Kloss Brian, Gawda Tomasz, Choy Brendon C, Zhang Zhening, Katewa Aditya, Larpthaveesarp Amara, Huang Eric J, Mooney Scott W J, Clarke Oliver B, Yee Sook Wah, Giacomini Kathleen M, Kossiakoff Anthony A, Quick Matthias, Arnold Thomas, Mancia Filippo

Alternating access of a bacterial homolog of neurotransmitter: sodium symporters determined from AlphaFold2 ensembles and DEER spectroscopy

利用 AlphaFold2 集合和双电子自旋共振光谱法确定细菌神经递质同源物的钠同向转运蛋白的交替访问

Schwartz, Alexandra C; Stein, Richard A; Gil-Iturbe, Eva; Quick, Matthias; Mchaourab, Hassane S

A novel 4-aminoquinoline chemotype with multistage antimalarial activity and lack of cross-resistance with PfCRT and PfMDR1 mutants

一种新型的4-氨基喹啉化学类型,具有多阶段抗疟活性,且与PfCRT和PfMDR1突变体无交叉耐药性。

Ferreira, Letícia Tiburcio; Cassiano, Gustavo Capatti; Alvarez, Luis Carlos Salazar; Okombo, John; Calit, Juliana; Fontinha, Diana; Gil-Iturbe, Eva; Coyle, Rachael; Andrade, Carolina Horta; Sunnerhagen, Per; Bargieri, Daniel Youssef; Prudêncio, Miguel; Quick, Matthias; Cravo, Pedro V; Lee, Marcus C S; Fidock, David A; Costa, Fabio Trindade Maranhão