日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Attenuation of Lipopolysaccharide-Induced Inflammatory Responses through Inhibition of the NF-κB Pathway and the Increased NRF2 Level by a Flavonol-Enriched n-Butanol Fraction from Uvaria alba

通过抑制 NF-κB 通路和提高 NRF2 水平,减弱脂多糖诱导的炎症反应,其中富含黄酮醇的紫紫薇正丁醇馏分来自

Kin Israel R Notarte, Mark Tristan J Quimque, Imee T Macaranas, Abbas Khan, Adriel M Pastrana, Oliver B Villaflores, Hans Christian P Arturo, Delfin Yñigo H Pilapil Iv, Sophia Morgan M Tan, Dong-Qing Wei, Arlette Wenzel-Storjohann, Deniz Tasdemir, Chia-Hung Yen, Seon Yeong Ji, Gi-Young Kim, Yung Hyu

Polyoxygenated Cyclohexenes from Uvaria grandiflora with Multi-Enzyme Targeting Properties Relevant in Type 2 Diabetes and Obesity

大花紫紫薇中的多氧环己烯具有与 2 型糖尿病和肥胖相关的多酶靶向特性

Mark Tristan J Quimque, Ryan Joseph Y Magsipoc, Lloyd Christian J Llames, Angeli Izza G Flores, Katherine Yasmin M Garcia, Andreas Ratzenböck, Hidayat Hussain, Allan Patrick G Macabeo

Myxobacterial depsipeptide chondramides interrupt SARS-CoV-2 entry by targeting its broad, cell tropic spike protein

粘细菌来源的缩肽软骨素通过靶向SARS-CoV-2病毒的广谱嗜细胞刺突蛋白来阻断病毒入侵。

Fernandez, Rey Arturo; Quimque, Mark Tristan; Notarte, Kin Israel; Manzano, Joe Anthony; Pilapil, Delfin Yñigo 4th; de Leon, Von Novi; San Jose, John Jeric; Villalobos, Omar; Muralidharan, Nisha Harur; Gromiha, M Michael; Brogi, Simone; Macabeo, Allan Patrick G

Antiproliferative and Cytotoxic Cytochalasins from Sparticola triseptata Inhibit Actin Polymerization and Aggregation

来自 Sparticola triseptata 的抗增殖和细胞毒性细胞松弛素抑制肌动蛋白聚合和聚集

Katherine Yasmin M Garcia, Mark Tristan J Quimque, Christopher Lambert, Katharina Schmidt, Gian Primahana, Theresia E B Stradal, Andreas Ratzenböck, Hans-Martin Dahse, Chayanard Phukhamsakda, Marc Stadler, Frank Surup, Allan Patrick G Macabeo

Potential Cancer- and Alzheimer's Disease-Targeting Phosphodiesterase Inhibitors from Uvaria alba: Insights from In Vitro and Consensus Virtual Screening

来自紫紫薇的潜在抗癌和抗阿尔茨海默病磷酸二酯酶抑制剂:体外和共识虚拟筛选的见解

Mark Tristan Quimque, Kin Israel Notarte, Arianne Letada, Rey Arturo Fernandez, Delfin Yñigo Pilapil 4th, Kirstin Rhys Pueblos, Jay Carl Agbay, Hans-Martin Dahse, Arlette Wenzel-Storjohann, Deniz Tasdemir, Abbas Khan, Dong-Qing Wei, Allan Patrick Gose Macabeo

Anti-HIV reverse transcriptase plant polyphenolic natural products with in silico inhibitory properties on seven non-structural proteins vital in SARS-CoV-2 pathogenesis

抗HIV逆转录酶植物多酚天然产物对七种在SARS-CoV-2致病机制中起关键作用的非结构蛋白具有计算机模拟抑制作用。

de Leon, Von Novi O; Manzano, Joe Anthony H; Pilapil, Delfin Yñigo H 4th; Fernandez, Rey Arturo T; Ching, James Kyle Anthony R; Quimque, Mark Tristan J; Agbay, Jay Carl M; Notarte, Kin Israel R; Macabeo, Allan Patrick G

Virtual screening-driven drug discovery of SARS-CoV2 enzyme inhibitors targeting viral attachment, replication, post-translational modification and host immunity evasion infection mechanisms

基于虚拟筛选的SARS-CoV-2酶抑制剂药物发现,靶向病毒附着、复制、翻译后修饰和宿主免疫逃逸感染机制。

Quimque, Mark Tristan J; Notarte, Kin Israel R; Fernandez, Rey Arturo T; Mendoza, Mark Andrew O; Liman, Rhenz Alfred D; Lim, Justin Allen K; Pilapil, Luis Agustin E; Ong, Jehiel Karsten H; Pastrana, Adriel M; Khan, Abbas; Wei, Dong-Qing; Macabeo, Allan Patrick G

COX Inhibitory and Cytotoxic Naphthoketal-Bearing Polyketides from Sparticola junci

来自 Sparticola junci 的具有 COX 抑制和细胞毒性的含萘缩酮的聚酮化合物

Katherine Yasmin M Garcia, Mark Tristan J Quimque, Gian Primahana, Andreas Ratzenböck, Mark Joseph B Cano, Jeremiah Francis A Llaguno, Hans-Martin Dahse, Chayanard Phukhamsakda, Frank Surup, Marc Stadler, Allan Patrick G Macabeo