日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structure-guided design of a PfCyRPA-based vaccine against blood-stage malaria

基于结构的PfCyRPA抗血期疟疾疫苗设计

Alam, Nawsad; Wolfle, Clare; Butkeviciute, Egle; Quinkert, Doris; King, Lloyd D W; Higgins, Matthew K

Lessons Learned About Digital Health Tool Acceptability Among Rural Older Adults: Systematic Review Guided by the Technology Acceptance Model

基于技术接受模型的系统性综述:农村老年人对数字健康工具接受度的经验教训

Siegel, Zachary M; Quinkert, Ellie; Pai, Jiya; Miller, Corinne H; Lewis, Marquita W

Development of clinical immunity to Plasmodium vivax following repeat controlled human malaria infection

反复控制性人类疟疾感染后,对间日疟原虫产生临床免疫力

Hou, Mimi M; Harding, Adam C; Barber, Natalie M; Kundu, Prasun; Bach, Florian A; Salkeld, Jo; Themistocleous, Yrene; Greenwood, Nicola M; Cho, Jee-Sun; Barrett, Jordan R; Nugent, Fay L; Rawlinson, Thomas A; Hodgson, Susanne H; Khozoee, Baktash; Mac Lochlainn, Dylan J; Cowan, Rachel E; Poulton, Ian D; Baker, Megan; Kingham, Lucy; Mitton, Celia H; Platt, Abigail; Lopez Ramon, Raquel; Ramos Lopez, Fernando; Thomas, Merin; Skinner, Katherine; Quinkert, Doris; Pipini, Dimitra; Lias, Amelia M; Bardelli, Martino; Edwards, Nick J; Donnellan, Francesca R; Biswas, Sumi; Rayner, Julian C; Nielsen, Carolyn M; Silk, Sarah E; Draper, Simon J; Nahrendorf, Wiebke; Spence, Philip J; Minassian, Angela M

Analysis of the diverse antigenic landscape of the malaria protein RH5 identifies a potent vaccine-induced human public antibody clonotype

对疟疾蛋白RH5多样化抗原图谱的分析,鉴定出一种强效的疫苗诱导的人类公共抗体克隆型。

Jordan R Barrett ,Dimitra Pipini ,Nathan D Wright ,Andrew J R Cooper ,Giacomo Gorini ,Doris Quinkert ,Amelia M Lias ,Hannah Davies ,Cassandra A Rigby ,Maya Aleshnick ,Barnabas G Williams ,William J Bradshaw ,Neil G Paterson ,Thomas Martinson ,Payton Kirtley ,Luc Picard ,Christine D Wiggins ,Francesca R Donnellan ,Lloyd D W King ,Lawrence T Wang ,Jonathan F Popplewell ,Sarah E Silk ,Jed de Ruiter Swain ,Katherine Skinner ,Vinayaka Kotraiah ,Amy R Noe ,Randall S MacGill ,C Richter King ,Ashley J Birkett ,Lorraine A Soisson ,Angela M Minassian ,Douglas A Lauffenburger ,Kazutoyo Miura ,Carole A Long ,Brandon K Wilder ,Lizbé Koekemoer ,Joshua Tan ,Carolyn M Nielsen ,Kirsty McHugh ,Simon J Draper

Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex

开发针对关键 RH5-CyRPA-RIPR 入侵复合物的改良血液阶段疟疾疫苗

Barnabas G Williams #, Lloyd D W King #, David Pulido, Doris Quinkert, Amelia M Lias, Sarah E Silk, Robert J Ragotte, Hannah Davies, Jordan R Barrett, Kirsty McHugh, Cassandra A Rigby, Daniel G W Alanine, Lea Barfod, Michael W Shea, Li An Cowley, Rebecca A Dabbs, David J Pattinson, Alexander D Dougl

Preclinical development of a stabilized RH5 virus-like particle vaccine that induces improved antimalarial antibodies

诱导增强抗疟抗体的稳定 RH5 病毒样颗粒疫苗的临床前开发

Lloyd D W King, David Pulido, Jordan R Barrett, Hannah Davies, Doris Quinkert, Amelia M Lias, Sarah E Silk, David J Pattinson, Ababacar Diouf, Barnabas G Williams, Kirsty McHugh, Ana Rodrigues, Cassandra A Rigby, Veronica Strazza, Jonathan Suurbaar, Chloe Rees-Spear, Rebecca A Dabbs, Andrew S Ishizu

Rational structure-guided design of a blood stage malaria vaccine immunogen presenting a single epitope from PfRH5

合理结构指导设计血液阶段疟疾疫苗免疫原,呈现来自 PfRH5 的单一表位

Thomas E Harrison #, Nawsad Alam #, Brendan Farrell #, Doris Quinkert, Amelia M Lias, Lloyd D W King, Lea K Barfod, Simon J Draper, Ivan Campeotto, Matthew K Higgins

Evaluation of the precision of the Plasmodium knowlesi growth inhibition assay for Plasmodium vivax Duffy-binding protein-based malaria vaccine development.

评估疟原虫生长抑制试验在间日疟原虫 Duffy 结合蛋白疟疾疫苗开发中的精确性

Mertens Jonas E, Rigby Cassandra A, Bardelli Martino, Quinkert Doris, Hou Mimi M, Diouf Ababacar, Silk Sarah E, Chitnis Chetan E, Minassian Angela M, Moon Robert W, Long Carole A, Draper Simon J, Miura Kazutoyo

A screen for Plasmodium falciparum sporozoite surface protein binding to human hepatocyte surface receptors identifies novel host-pathogen interactions

一项针对恶性疟原虫子孢子表面蛋白与人肝细胞表面受体结合的筛选,揭示了新的宿主-病原体相互作用。

Rameswara R Segireddy,Hugo Belda,Annie S P Yang,Kirsten Dundas #,Julia Knoeckel #,Francis Galaway,Laura Wood,Doris Quinkert,Ellen Knuepfer,Moritz Treeck,Gavin J Wright ,Alexander D Douglas

The dual action of human antibodies specific to Plasmodium falciparum PfRH5 and PfCyRPA: Blocking invasion and inactivating extracellular merozoites

针对恶性疟原虫 PfRH5 和 PfCyRPA 的人类特异性抗体的双重作用:阻断入侵和灭活细胞外裂殖子

Weiss, Greta E; Ragotte, Robert J; Quinkert, Doris; Lias, Amelia M; Dans, Madeline G; Boulet, Coralie; Looker, Oliver; Ventura, Olivia D; Williams, Barnabas G; Crabb, Brendan S; Draper, Simon J; Gilson, Paul R