PMX464, a thiol-reactive quinol and putative thioredoxin inhibitor, inhibits NF-kappaB-dependent proinflammatory activation of alveolar epithelial cells.
PMX464 是一种硫醇反应性醌类化合物,被认为是硫氧还蛋白抑制剂,它能抑制 NF-κB 依赖的肺泡上皮细胞促炎活化
期刊:British Journal of Pharmacology
影响因子:7.7
doi:10.1038/bjp.2008.258
Callister M E, Pinhu L, Catley M C, Westwell A D, Newton R, Leaver S K, Quinlan G J, Evans T W, Griffiths M J, Burke-Gaffney A