日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Generation of FX-/- and Gmds-/- CHOZN host cell lines for the production of afucosylated therapeutic antibodies

生成 FX-/- 和 Gmds-/- CHOZN 宿主细胞系以生产无岩藻糖基化治疗性抗体

Weiyi Liu, Roshan Padmashali, Omar Quintero Monzon, Dianna Lundberg, Shan Jin, Brian Dwyer, Yun-Jung Lee, Anisha Korde, Sophia Park, Clark Pan, Bohong Zhang

Dynamic analysis of amyloid β-protein in behaving mice reveals opposing changes in ISF versus parenchymal Aβ during age-related plaque formation

对行为小鼠中淀粉样β蛋白的动态分析表明,在与年龄相关的斑块形成过程中,ISF 与实质 Aβ 发生了相反的变化

Soyon Hong, Omar Quintero-Monzon, Beth L Ostaszewski, Daniel R Podlisny, William T Cavanaugh, Ting Yang, David M Holtzman, John R Cirrito, Dennis J Selkoe

Dissociation between the processivity and total activity of γ-secretase: implications for the mechanism of Alzheimer's disease-causing presenilin mutations

γ-分泌酶的加工活性与总活性之间的分离:对阿尔茨海默病致病早老素突变机制的启示

Quintero-Monzon, Omar; Martin, Morgan M; Fernandez, Marty A; Cappello, Christina A; Krzysiak, Amanda J; Osenkowski, Pamela; Wolfe, Michael S

Reconstitution and dissection of the 600-kDa Srv2/CAP complex: roles for oligomerization and cofilin-actin binding in driving actin turnover

600 kDa Srv2/CAP复合物的重组和解析:寡聚化和cofilin-肌动蛋白结合在驱动肌动蛋白周转中的作用

Quintero-Monzon, Omar; Jonasson, Erin M; Bertling, Enni; Talarico, Lou; Chaudhry, Faisal; Sihvo, Maarit; Lappalainen, Pekka; Goode, Bruce L

Structural and functional dissection of the Abp1 ADFH actin-binding domain reveals versatile in vivo adapter functions

对 Abp1 ADFH 肌动蛋白结合域的结构和功能分析揭示了其在体内发挥的多种衔接功能。

Quintero-Monzon, Omar; Rodal, Avital A; Strokopytov, Boris; Almo, Steven C; Goode, Bruce L

A high-affinity interaction with ADP-actin monomers underlies the mechanism and in vivo function of Srv2/cyclase-associated protein

与 ADP-肌动蛋白单体的高亲和力相互作用是 Srv2/环化酶相关蛋白的机制和体内功能的基础

Pieta K Mattila, Omar Quintero-Monzon, Jamie Kugler, James B Moseley, Steven C Almo, Pekka Lappalainen, Bruce L Goode