Ibrutinib modulates the immunosuppressive CLL microenvironment through STAT3-mediated suppression of regulatory B-cell function and inhibition of the PD-1/PD-L1 pathway
伊布替尼通过 STAT3 介导的调节性 B 细胞功能抑制和 PD-1/PD-L1 通路抑制来调节免疫抑制性 CLL 微环境
期刊:Leukemia
影响因子:12.8
doi:10.1038/leu.2017.304
K Kondo, H Shaim, P A Thompson, J A Burger, M Keating, Z Estrov, D Harris, E Kim, A Ferrajoli, M Daher, R Basar, M Muftuoglu, N Imahashi, A Alsuliman, C Sobieski, E Gokdemir, W Wierda, N Jain, E Liu, E J Shpall, K Rezvani
