日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The anti-Müllerian hormone prodomain is displaced from the hormone/prodomain complex upon bivalent binding to the hormone receptor

抗苗勒氏管激素前结构域与激素受体二价结合后,从激素/前结构域复合物中移出

Richard L Cate, Nathalie di Clemente, Chrystèle Racine, Nigel P Groome, R Blake Pepinsky, Adrian Whitty

Functional activity of anti-LINGO-1 antibody opicinumab requires target engagement at a secondary binding site

抗LINGO-1抗体opicinumab的功能活性需要其与二级结合位点的靶标结合。

Karl J M Hanf ,Joseph W Arndt ,YuTing Liu ,Bang Jian Gong ,Mia Rushe ,Richelle Sopko ,Ramiro Massol ,Benjamin Smith ,Yan Gao ,Isin Dalkilic-Liddle ,Xinhua Lee ,Shanell Mojta ,Zhaohui Shao ,Sha Mi ,R Blake Pepinsky

Structural and kinetic basis for the selectivity of aducanumab for aggregated forms of amyloid-β

Aducanumab 对聚集形式的淀粉样β蛋白的选择性的结构和动力学基础

Joseph W Arndt, Fang Qian, Benjamin A Smith, Chao Quan, Krishna Praneeth Kilambi, Martin W Bush, Thomas Walz, R Blake Pepinsky, Thierry Bussière, Stefan Hamann, Thomas O Cameron, Paul H Weinreb

Dynamic structural changes are observed upon collagen and metal ion binding to the integrin α1 I domain

胶原蛋白和金属离子与整合素 α1 I 结构域结合后可观察到动态结构变化

Paul H Weinreb, Sheng Li, Sharon X Gao, Tong Liu, R Blake Pepinsky, Justin A Caravella, Jun H Lee, Virgil L Woods Jr

Processing of anti-mullerian hormone regulates receptor activation by a mechanism distinct from TGF-beta

抗苗勒氏管激素的加工通过不同于 TGF-β 的机制调节受体活化

Nathalie di Clemente, Soazik P Jamin, Alexey Lugovskoy, Paul Carmillo, Christian Ehrenfels, Jean-Yves Picard, Adrian Whitty, Nathalie Josso, R Blake Pepinsky, Richard L Cate

Recombinant GDNF: tetanus toxin fragment C fusion protein produced from insect cells

重组GDNF:昆虫细胞产生的破伤风毒素片段C融合蛋白

Jianhong Li, Ru-Ju Chian, Ilknur Ay, Samuel A Celia, Brenda B Kashi, Eric Tamrazian, Jonathan C Matthews, Mary P Remington, R Blake Pepinsky, Paul S Fishman, Robert H Brown Jr, Jonathan W Francis