日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The cellular esterase FrmB controls metabolic homeostasis and small colony variant formation in Staphylococcus aureus

细胞酯酶FrmB控制金黄色葡萄球菌的代谢稳态和小菌落变异体的形成

O'Brien, Kelsey A; Miller, Justin J; Johnson, R Jeremy; Hoops, Geoffrey C; John, Audrey R Odom

Shifting Mycobacterial Serine Hydrolase Activity Visualized Using Multi-Layer In-Gel Activity Assays

使用多层凝胶内活性测定法可视化转移分枝杆菌丝氨酸水解酶活性

Allison L Goss, Renee E Shudick, R Jeremy Johnson

Sequence and Structural Motifs Controlling the Broad Substrate Specificity of the Mycobacterial Hormone-Sensitive Lipase LipN

控制分枝杆菌激素敏感脂肪酶 LipN 广泛底物特异性的序列和结构基序

Daniel E Schemenauer, Emily H Pool, Stephanie N Raynor, Gabriela P Ruiz, Leah M Goehring, Andrew J Koelper, Madeleine A Wilson, Anthony J Durand Jr, Elexi C Kourtoglou, Erik M Larsen, Luke D Lavis, John J Esteb, Geoffrey C Hoops, R Jeremy Johnson

PAK6-mediated phosphorylation of PPP2R2C regulates LRRK2-PP2A complex formation

PAK6 介导的 PPP2R2C 磷酸化调节 LRRK2-PP2A 复合物的形成

Lucia Iannotta, Marco Emanuele, Giulia Favetta, Giulia Tombesi, Laurine Vandewynckel, Antonio Jesús Lara Ordóñez, Jean-Michel Saliou, Matthieu Drouyer, William Sibran, Laura Civiero, R Jeremy Nichols, Panagiotis S Athanasopoulos, Arjan Kortholt, Marie-Christine Chartier-Harlin, Elisa Greggio, Jean-M

Evaluation of Current Methods to Detect Cellular Leucine-Rich Repeat Kinase 2 (LRRK2) Kinase Activity

评估当前检测细胞富含亮氨酸重复激酶 2 (LRRK2) 激酶活性的方法

Belén Fernández, Vinita G Chittoor-Vinod, Jillian H Kluss, Kaela Kelly, Nicole Bryant, An Phu Tran Nguyen, Syed A Bukhari, Nathan Smith, Antonio Jesús Lara Ordóñez, Elena Fdez, Marie-Christine Chartier-Harlin, Thomas J Montine, Mark A Wilson, Darren J Moore, Andrew B West, Mark R Cookson, R Jeremy N

Discovery of G2019S-Selective Leucine Rich Repeat Protein Kinase 2 inhibitors with in vivo efficacy

发现具有体内疗效的 G2019S-选择性亮氨酸富集重复蛋白激酶 2 抑制剂

Robert K Leśniak, R Jeremy Nichols, Marcus Schonemann, Jing Zhao, Chandresh R Gajera, William L Fitch, Grace Lam, Khanh C Nguyen, Mark Smith, Thomas J Montine

A Phosphosite Mutant Approach on LRRK2 Links Phosphorylation and Dephosphorylation to Protective and Deleterious Markers, Respectively

LRRK2磷酸化位点突变方法将磷酸化和去磷酸化分别与保护性和有害性标记联系起来

Marchand, Antoine; Sarchione, Alessia; Athanasopoulos, Panagiotis S; Roy, Hélène Bauderlique-Le; Goveas, Liesel; Magnez, Romain; Drouyer, Matthieu; Emanuele, Marco; Ho, Franz Y; Liberelle, Maxime; Melnyk, Patricia; Lebègue, Nicolas; Thuru, Xavier; Nichols, R Jeremy; Greggio, Elisa; Kortholt, Arjan; Galli, Thierry; Chartier-Harlin, Marie-Christine; Taymans, Jean-Marc

Development of mutation-selective LRRK2 kinase inhibitors as precision medicine for Parkinson's disease and other diseases for which carriers are at increased risk

开发突变选择性LRRK2激酶抑制剂,作为帕金森病和其他携带者风险增加的疾病的精准治疗药物。

Lesniak, Robert K; Nichols, R Jeremy; Montine, Thomas J

Correction: Structure-guided microbial targeting of antistaphylococcal prodrugs

更正:抗葡萄球菌前药的结构导向微生物靶向治疗

Miller, Justin J; Shah, Ishaan T; Hatten, Jayda; Barekatain, Yasaman; Mueller, Elizabeth A; Moustafa, Ahmed M; Edwards, Rachel L; Dowd, Cynthia S; Hoops, Geoffrey C; Johnson, R Jeremy; Planet, Paul; Muller, Florian L; Jez, Joseph; Odom John, Audrey R

Structure-guided microbial targeting of antistaphylococcal prodrugs

基于结构的抗葡萄球菌前药的微生物靶向治疗

Justin J Miller,Ishaan T Shah,Jayda Hatten,Yasaman Barekatain,Elizabeth A Mueller,Ahmed M Moustafa,Rachel L Edwards,Cynthia S Dowd,Geoffrey C Hoops,R Jeremy Johnson,Paul J Planet,Florian L Muller,Joseph M Jez,Audrey R Odom John