日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Tongue orthotopic xenografts to study fusion-negative rhabdomyosarcoma invasion and metastasis in live animals

利用舌原位异种移植研究融合阴性横纹肌肉瘤在活体动物中的侵袭和转移

Sarah M Hammoudeh ,Yeap Ng ,Bih-Rong Wei ,Thomas D Madsen ,Mukesh P Yadav ,R Mark Simpson ,Roberto Weigert ,Paul A Randazzo

Fusion-negative rhabdomyosarcoma orthotopic tongue xenografts for study of invasion, intravasation and metastasis in live animals

融合阴性横纹肌肉瘤原位舌异种移植用于研究活体动物的侵袭、渗出和转移

Sarah M Hammoudeh, Yeap Ng, Bih-Rong Wei, Thomas D Madsen, R Mark Simpson, Roberto Weigert, Paul A Randazzo

Host CLIC4 expression in the tumor microenvironment is essential for breast cancer metastatic competence

肿瘤微环境中宿主 CLIC4 的表达对乳腺癌转移能力至关重要

Vanesa C Sanchez, Howard H Yang, Alayna Craig-Lucas, Wendy Dubois, Brandi L Carofino, Justin Lack, Jennifer E Dwyer, R Mark Simpson, Christophe Cataisson, Max P Lee, Ji Luo, Kent W Hunter, Stuart H Yuspa

Nuclear pore protein NUP210 depletion suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response

核孔蛋白 NUP210 的消耗通过异染色质介导的肿瘤细胞机械反应破坏来抑制转移

Ruhul Amin, Anjali Shukla, Jacqueline Jufen Zhu, Sohyoung Kim, Ping Wang, Simon Zhongyuan Tian, Andy D Tran, Debasish Paul, Steven D Cappell, Sandra Burkett, Huaitian Liu, Maxwell P Lee, Michael J Kruhlak, Jennifer E Dwyer, R Mark Simpson, Gordon L Hager, Yijun Ruan, Kent W Hunter

Hypomorphic mTOR Downregulates CDK6 and Delays Thymic Pre-T LBL Tumorigenesis

低效 mTOR 下调 CDK6 并延迟胸腺 Pre-T LBL 肿瘤发生

Joy M Gary #, John K Simmons #, Jinfei Xu #, Shuling Zhang, Tyler J Peat, Nicholas Watson, Benjamin J Gamache, Ke Zhang, Alexander L Kovalchuk, Aleksandra M Michalowski, Jin-Qiu Chen, Tuddow Thaiwong, Matti Kiupel, Snehal Gaikwad, Maudeline Etienne, R Mark Simpson, Wendy Dubois, Joseph R Testa, Beve

A Revised Diagnostic Classification of Canine Glioma: Towards Validation of the Canine Glioma Patient as a Naturally Occurring Preclinical Model for Human Glioma

犬胶质瘤诊断分类修订版:验证犬胶质瘤患者作为人类胶质瘤自然发生的临床前模型

Jennifer W Koehler, Andrew D Miller, C Ryan Miller, Brian Porter, Kenneth Aldape, Jessica Beck, Daniel Brat, Ingrid Cornax, Kara Corps, Chad Frank, Caterina Giannini, Craig Horbinski, Jason T Huse, M Gerard O'Sullivan, Daniel R Rissi, R Mark Simpson, Kevin Woolard, Joanna H Shih, Christina Mazcko, M

cFOS-SOX9 Axis Reprograms Bone Marrow-Derived Mesenchymal Stem Cells into Chondroblastic Osteosarcoma

cFOS-SOX9 轴将骨髓间充质干细胞重新编程为软骨母细胞性骨肉瘤

Yunlong He, Wentao Zhu, Min Hwa Shin, Joy Gary, Chengyu Liu, Wendy Dubois, Shelley B Hoover, Shunlin Jiang, Eryney Marrogi, Beverly Mock, R Mark Simpson, Jing Huang

Synergistic targeted inhibition of MEK and dual PI3K/mTOR diminishes viability and inhibits tumor growth of canine melanoma underscoring its utility as a preclinical model for human mucosal melanoma

MEK 和双重 PI3K/mTOR 的协同靶向抑制可降低犬黑色素瘤的生存力并抑制其肿瘤生长,凸显了其作为人类粘膜黑色素瘤临床前模型的实用性

Bih-Rong Wei, Helen T Michael, Charles H C Halsey, Cody J Peer, Amit Adhikari, Jennifer E Dwyer, Shelley B Hoover, Rajaa El Meskini, Serguei Kozlov, Zoe Weaver Ohler, William D Figg, Glenn Merlino, R Mark Simpson

Bioluminescent imaging of ABCG2 efflux activity at the blood-placenta barrier

血胎盘屏障处 ABCG2 外排活性的生物发光成像

Jeyan S Kumar, Bih-Rong Wei, James P Madigan, R Mark Simpson, Matthew D Hall, Michael M Gottesman

Loss of MIG6 Accelerates Initiation and Progression of Mutant Epidermal Growth Factor Receptor-Driven Lung Adenocarcinoma

MIG6 的缺失加速了突变表皮生长因子受体驱动的肺腺癌的发生和进展

Tapan K Maity, Abhilash Venugopalan, Ilona Linnoila, Constance M Cultraro, Andreas Giannakou, Roxanne Nemati, Xu Zhang, Joshua D Webster, Daniel Ritt, Sarani Ghosal, Heinz Hoschuetzky, R Mark Simpson, Romi Biswas, Katerina Politi, Deborah K Morrison, Harold E Varmus, Udayan Guha