R Steven Conlan相关文献与解析，生知库 | 链接生命科学的每一步

Lydia C Powell, Marcos Quintela, David W James, Emenike Onyido, David Howard, Kadie Edwards, Jordan L Turney, Charlotte R Morgan, Jenny Worthington, Nicole Williams, Alexander Dulebo, Heiko Haschke, Deyarina Gonzalez, R Steven Conlan, Lewis W Francis

肿瘤

卵巢癌

发表日期：2025

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Adipocyte derived exosomes promote cell invasion and challenge paclitaxel efficacy in ovarian cancer

脂肪细胞衍生的外泌体促进细胞侵袭并挑战紫杉醇在卵巢癌中的疗效

期刊:Cell Communication and Signaling

影响因子:8.2

doi:10.1186/s12964-024-01806-4

Michael Ellis Williams, David Howard, Claire Donnelly, Fereshteh Izadi, Jezabel Garcia Parra, Megan Pugh, Kadie Edwards, Kerryn Lutchman-Sigh, Sadie Jones, Lavinia Margarit, Lewis Francis, R Steven Conlan, Francesca Taraballi, Deyarina Gonzalez

Homeobox regulator Wilms Tumour 1 is displaced by androgen receptor at cis-regulatory elements in the endometrium of PCOS patients

PCOS 患者子宫内膜中顺式调节元件处的同源框调节剂 Wilms 肿瘤 1 被雄激素受体取代

期刊:Frontiers in Endocrinology

影响因子:

doi:10.3389/fendo.2024.1368494

David W James, Marcos Quintela, Lisa Lucini, Noor K Alkafri, Gareth D Healey, Kinza Younas, Adnan Bunkheila, Lavinia Margarit, Lewis W Francis, Deyarina Gonzalez, R Steven Conlan

肿瘤

发表日期：2024

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Selenium nanoparticles modulate histone methylation via lysine methyltransferase activity and S-adenosylhomocysteine depletion

硒纳米粒子通过赖氨酸甲基转移酶活性和 S-腺苷酸同型半胱氨酸耗竭调节组蛋白甲基化

期刊:Redox Biology

影响因子:10.7

doi:10.1016/j.redox.2023.102641

Benoit Toubhans, Nour Alkafri, Marcos Quintela, David W James, Caroline Bissardon, Salvatore Gazze, Franziska Knodel, Olivier Proux, Alexandra T Gourlan, Philipp Rathert, Sylvain Bohic, Deyarina Gonzalez, Lewis W Francis, Laurent Charlet, R Steven Conlan

In silico enhancer mining reveals SNS-032 and EHMT2 inhibitors as therapeutic candidates in high-grade serous ovarian cancer

计算机辅助增强子挖掘揭示SNS-032和EHMT2抑制剂是高级别浆液性卵巢癌的候选治疗药物

期刊:British Journal of Cancer

影响因子:6.4

doi:10.1038/s41416-023-02274-2

Marcos Quintela # ，David W James # ，Jetzabel Garcia ，Kadie Edwards ，Lavinia Margarit ，Nagindra Das ，Kerryn Lutchman-Singh ，Amy L Beynon ，Inmaculada Rioja ，Rab K Prinjha ，Nicola R Harker ，Deyarina Gonzalez ，R Steven Conlan ，Lewis W Francis

Intracellular Fate of Sub-Toxic Concentration of Functionalized Selenium Nanoparticles in Aggressive Prostate Cancer Cells

亚毒性浓度功能化硒纳米粒子在侵袭性前列腺癌细胞中的细胞内命运

期刊:Nanomaterials

影响因子:

doi:10.3390/nano13232999

Caroline Bissardon, Olivier Proux, Salvatore Andrea Gazze, Odile Filhol, Benoît Toubhans, Lucie Sauzéat, Sylvain Bouchet, Aled R Lewis, Thierry Maffeis, Jean-Louis Hazemann, Sam Bayat, Peter Cloetens, R Steven Conlan, Laurent Charlet, Sylvain Bohic

Bromodomain inhibitor i-BET858 triggers a unique transcriptional response coupled to enhanced DNA damage, cell cycle arrest and apoptosis in high-grade ovarian carcinoma cells

溴结构域抑制剂 i-BET858 可触发独特的转录反应，并伴有高级别卵巢癌细胞中 DNA 损伤增强、细胞周期停滞和细胞凋亡

期刊:Clinical Epigenetics

影响因子:

doi:10.1186/s13148-023-01477-x

Marcos Quintela, David W James, Agne Pociute, Lydia Powell, Kadie Edwards, Zoe Coombes, Jetzabel Garcia, Neil Garton, Nagindra Das, Kerryn Lutchman-Singh, Lavinia Margarit, Amy L Beynon, Inmaculada Rioja, Rab K Prinjha, Nicola R Harker, Deyarina Gonzalez, R Steven Conlan, Lewis W Francis

Dinaciclib as an effective pan-cyclin dependent kinase inhibitor in platinum resistant ovarian cancer

Dinaciclib 是治疗铂耐药性卵巢癌的有效泛细胞周期蛋白依赖性激酶抑制剂

期刊:Frontiers in Oncology

影响因子:3.5

doi:10.3389/fonc.2022.1014280

David Howard, David James, Jezabel Garcia-Parra, Belen Pan-Castillo, Jenny Worthington, Nicole Williams, Zoe Coombes, Sophie Colleen Rees, Kerryn Lutchman-Singh, Lewis W Francis, Paul Rees, Lavinia Margarit, R Steven Conlan, Deyarina Gonzalez

Highly glycosylated MUC1 mediates high affinity L-selectin binding at the human endometrial surface

高度糖基化的 MUC1 介导人类子宫内膜表面的高亲和力 L-选择素结合

期刊:Journal of Nanobiotechnology

影响因子:10.6

doi:10.1186/s12951-021-00793-9

Lewis W Francis, Seydou N Yao, Lydia C Powell, Sean Griffiths, Alexander Berquand, Thomas Piasecki, William Howe, Andrea S Gazze, Mary C Farach-Carson, Pamela Constantinou, Daniel Carson, Lavinia Margarit, Deya Gonzalez, R Steven Conlan

MUC1

发表日期：2021

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Progesterone Metabolism by Human and Rat Hepatic and Intestinal Tissue

人类和大鼠肝脏和肠道组织的孕酮代谢

期刊:Pharmaceutics

影响因子:4.9

doi:10.3390/pharmaceutics13101707

Zoe Coombes, Katie Plant, Cristina Freire, Abdul W Basit, Philip Butler, R Steven Conlan, Deyarina Gonzalez

代谢

发表日期：2021

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Cisplatin resistance alters ovarian cancer spheroid formation and impacts peritoneal invasion

顺铂耐药性改变卵巢癌球体形成并影响腹膜侵袭

Adipocyte derived exosomes promote cell invasion and challenge paclitaxel efficacy in ovarian cancer

脂肪细胞衍生的外泌体促进细胞侵袭并挑战紫杉醇在卵巢癌中的疗效

Homeobox regulator Wilms Tumour 1 is displaced by androgen receptor at cis-regulatory elements in the endometrium of PCOS patients

PCOS 患者子宫内膜中顺式调节元件处的同源框调节剂 Wilms 肿瘤 1 被雄激素受体取代

Selenium nanoparticles modulate histone methylation via lysine methyltransferase activity and S-adenosylhomocysteine depletion

硒纳米粒子通过赖氨酸甲基转移酶活性和 S-腺苷酸同型半胱氨酸耗竭调节组蛋白甲基化

In silico enhancer mining reveals SNS-032 and EHMT2 inhibitors as therapeutic candidates in high-grade serous ovarian cancer

计算机辅助增强子挖掘揭示SNS-032和EHMT2抑制剂是高级别浆液性卵巢癌的候选治疗药物

Intracellular Fate of Sub-Toxic Concentration of Functionalized Selenium Nanoparticles in Aggressive Prostate Cancer Cells

亚毒性浓度功能化硒纳米粒子在侵袭性前列腺癌细胞中的细胞内命运

Bromodomain inhibitor i-BET858 triggers a unique transcriptional response coupled to enhanced DNA damage, cell cycle arrest and apoptosis in high-grade ovarian carcinoma cells

溴结构域抑制剂 i-BET858 可触发独特的转录反应，并伴有高级别卵巢癌细胞中 DNA 损伤增强、细胞周期停滞和细胞凋亡

Dinaciclib as an effective pan-cyclin dependent kinase inhibitor in platinum resistant ovarian cancer

Dinaciclib 是治疗铂耐药性卵巢癌的有效泛细胞周期蛋白依赖性激酶抑制剂

Highly glycosylated MUC1 mediates high affinity L-selectin binding at the human endometrial surface

高度糖基化的 MUC1 介导人类子宫内膜表面的高亲和力 L-选择素结合

Progesterone Metabolism by Human and Rat Hepatic and Intestinal Tissue

人类和大鼠肝脏和肠道组织的孕酮代谢