A parallel genome-wide mRNA and microRNA profiling of the frontal cortex of HIV patients with and without HIV-associated dementia shows the role of axon guidance and downstream pathways in HIV-mediated neurodegeneration

对伴有和不伴有HIV相关痴呆的HIV感染者额叶皮层进行全基因组mRNA和microRNA平行分析，揭示了轴突导向及其下游通路在HIV介导的神经退行性变中的作用。