The lncRNA Firre anchors the inactive X chromosome to the nucleolus by binding CTCF and maintains H3K27me3 methylation
lncRNA Firre通过与CTCF结合将失活的X染色体锚定在核仁上,并维持H3K27me3甲基化。
期刊:Genome Biology
影响因子:9.4
doi:10.1186/s13059-015-0618-0
Yang, Fan; Deng, Xinxian; Ma, Wenxiu; Berletch, Joel B; Rabaia, Natalia; Wei, Gengze; Moore, James M; Filippova, Galina N; Xu, Jun; Liu, Yajuan; Noble, William S; Shendure, Jay; Disteche, Christine M