日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Intracellular Antibodies for Drug Discovery and as Drugs of the Future

用于药物发现和未来药物的细胞内抗体

Rabbitts, T H

Conformational flexibility of the oncogenic protein LMO2 primes the formation of the multi-protein transcription complex.

致癌蛋白LMO2的构象灵活性促进了多蛋白转录复合物的形成

Sewell H, Tanaka T, El Omari K, Mancini E J, Cruz A, Fernandez-Fuentes N, Chambers J, Rabbitts T H

Null mutation of the Lmo4 gene or a combined null mutation of the Lmo1/Lmo3 genes causes perinatal lethality, and Lmo4 controls neural tube development in mice

Lmo4基因的缺失突变或Lmo1/Lmo3基因的联合缺失突变会导致围产期死亡,而Lmo4基因控制小鼠的神经管发育。

Tse, E; Smith, A J H; Hunt, S; Lavenir, I; Forster, A; Warren, A J; Grutz, G; Foroni, L; Carlton, M B L; Colledge, W H; Boehm, T; Rabbitts, T H

The oncogenic LIM-only transcription factor Lmo2 regulates angiogenesis but not vasculogenesis in mice

致癌的仅含LIM结构域的转录因子Lmo2调控小鼠的血管生成,但不调控血管形成。

Yamada, Y; Pannell, R; Forster, A; Rabbitts, T H

Structural basis for the heterodimeric interaction between the acute leukaemia-associated transcription factors AML1 and CBFbeta

急性白血病相关转录因子AML1和CBFβ异二聚体相互作用的结构基础

Warren, A J; Bravo, J; Williams, R L; Rabbitts, T H

Tumorigenesis in mice with a fusion of the leukaemia oncogene Mll and the bacterial lacZ gene

小鼠中白血病癌基因 Mll 与细菌 lacZ 基因融合引起的肿瘤发生

Dobson, C L; Warren, A J; Pannell, R; Forster, A; Rabbitts, T H

Masked antisense: a molecular configuration for discriminating similar RNA targets

掩蔽反义:一种用于区分相似RNA靶标的分子构型

Stocks, M R; Rabbitts, T H

Inter-chromosomal recombination of Mll and Af9 genes mediated by cre-loxP in mouse development

小鼠发育过程中由cre-loxP介导的Mll和Af9基因的染色体间重组

Collins, E C; Pannell, R; Simpson, E M; Forster, A; Rabbitts, T H

Selection of antibodies for intracellular function using a two-hybrid in vivo system

利用双杂交体内系统筛选具有细胞内功能的抗体

Visintin, M; Tse, E; Axelson, H; Rabbitts, T H; Cattaneo, A

The mll-AF9 gene fusion in mice controls myeloproliferation and specifies acute myeloid leukaemogenesis

小鼠中的mll-AF9基因融合控制骨髓增殖并决定急性髓系白血病的发生。

Dobson, C L; Warren, A J; Pannell, R; Forster, A; Lavenir, I; Corral, J; Smith, A J; Rabbitts, T H