Ectopic Methylation of a Single Persistently Unmethylated CpG in the Promoter of the Vitellogenin Gene Abolishes Its Inducibility by Estrogen through Attenuation of Upstream Stimulating Factor Binding

卵黄蛋白基因启动子中单个持续未甲基化的 CpG 异位甲基化通过减弱上游刺激因子结合消除了雌激素对其的诱导作用